分泌型磷脂酶A2的结构与催化机制 - Suppr

Suppr

超能文献

Structure and catalytic mechanism of secretory phospholipases A2.

作者信息

Scott D L, Sigler P B

机构信息

Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06510.

出版信息

Adv Protein Chem. 1994;45:53-88. doi: 10.1016/s0065-3233(08)60638-5.

DOI:10.1016/s0065-3233(08)60638-5

PMID:8154374

Abstract

摘要

相似文献

Structure and catalytic mechanism of secretory phospholipases A2.分泌型磷脂酶A2的结构与催化机制

Adv Protein Chem. 1994;45:53-88. doi: 10.1016/s0065-3233(08)60638-5.

Secretory phospholipase A2 from Arabidopsis thaliana: insights into the three-dimensional structure and the amino acids involved in catalysis.来自拟南芥的分泌型磷脂酶A2：对三维结构及催化相关氨基酸的深入了解。

Biochemistry. 2006 May 9;45(18):5687-94. doi: 10.1021/bi052563z.

Structural basis for low catalytic activity in Lys49 phospholipases A2--a hypothesis: the crystal structure of piratoxin II complexed to fatty acid.49位赖氨酸磷脂酶A2低催化活性的结构基础——一种假说：与脂肪酸复合的piratoxin II晶体结构

Biochemistry. 2001 Jan 9;40(1):28-36. doi: 10.1021/bi0010470.

A molecular model for interfacial activation in phospholipase A2.磷脂酶A2界面激活的分子模型

FEBS Lett. 1997 Mar 10;404(2-3):159-63. doi: 10.1016/s0014-5793(97)00119-1.

X-ray structure of phospholipase A2 complexed with a substrate-derived inhibitor.与一种底物衍生抑制剂复合的磷脂酶A2的X射线结构

Nature. 1990 Oct 18;347(6294):689-91. doi: 10.1038/347689a0.

Crystal structure of cobra-venom phospholipase A2 in a complex with a transition-state analogue.眼镜蛇毒磷脂酶A2与过渡态类似物复合物的晶体结构

Science. 1990 Dec 14;250(4987):1560-3. doi: 10.1126/science.2274787.

Crystal structure of bee-venom phospholipase A2 in a complex with a transition-state analogue.

Science. 1990 Dec 14;250(4987):1563-6. doi: 10.1126/science.2274788.

The electrostatic basis for the interfacial binding of secretory phospholipases A2.分泌型磷脂酶A2界面结合的静电基础

Biophys J. 1994 Aug;67(2):493-504. doi: 10.1016/S0006-3495(94)80546-6.

Secretory phospholipases A2.分泌型磷脂酶A2

J Lipid Mediat Cell Signal. 1995 Oct;12(2-3):119-30. doi: 10.1016/0929-7855(95)00013-g.

Sequence homology between Wingless/Wnt-1 and a lipid-binding domain in secreted phospholipase A2.无翅型/无翅型小鼠乳腺癌病毒整合位点家族成员1（Wingless/Wnt-1）与分泌型磷脂酶A2中一个脂质结合结构域之间的序列同源性。

Curr Biol. 1999 May 20;9(10):R353-5. doi: 10.1016/s0960-9822(99)80225-5.

引用本文的文献

Biochemical, Kinetic and Biological Properties of Group V Phospholipase A2 from Dromedary.从单峰驼中提取的 V 组磷酸脂酶 A2 的生化、动力学和生物学特性

Molecules. 2022 May 26;27(11):3437. doi: 10.3390/molecules27113437.

Functional Annotation from Structural Homology.功能注释来自结构同源性。

Methods Mol Biol. 2022;2349:215-257. doi: 10.1007/978-1-0716-1585-0_11.

Inhibition of Neurotoxic Secretory Phospholipases A(2) Enzymatic, Edematogenic, and Myotoxic Activities by Harpalycin 2, an Isoflavone Isolated from Harpalyce brasiliana Benth.巴西哈伯拉辛（Harpalyce brasiliana Benth.）中分离得到的异黄酮哈帕利辛 2 抑制神经毒性分泌型磷脂酶 A2 的酶活性、水肿形成活性和肌毒性活性

Evid Based Complement Alternat Med. 2012;2012:987517. doi: 10.1155/2012/987517. Epub 2012 Jul 31.

Orientation and conformation of lipids in crystals of transmembrane proteins.跨膜蛋白晶体中脂质的取向和构象。

Eur Biophys J. 2013 Mar;42(2-3):119-46. doi: 10.1007/s00249-012-0816-6. Epub 2012 May 30.

Structural analysis of secretory phospholipase A2 from Clonorchis sinensis: therapeutic implications for hepatic fibrosis.华支睾吸虫分泌型磷脂酶 A2 的结构分析：对肝纤维化的治疗意义。

J Mol Model. 2012 Jul;18(7):3139-45. doi: 10.1007/s00894-011-1333-8. Epub 2012 Jan 4.

Purification and biochemical characterization of a secreted group IIA chicken intestinal phospholipase A₂.分泌型 IIA 鸡肠磷脂酶 A₂的纯化和生化特性分析。

Lipids Health Dis. 2011 Feb 1;10:27. doi: 10.1186/1476-511X-10-27.

Modulation of the pharmacological activities of secretory phospholipase A2 from Crotalus durissus cascavella induced by naringin.纳吉灵对矛头蝮蛇毒源分泌型磷脂酶 A2 的药理学活性的调控作用。

Molecules. 2011 Jan 18;16(1):738-61. doi: 10.3390/molecules16010738.

Inhibition of secreted phospholipases A₂ by 2-oxoamides based on α-amino acids: Synthesis, in vitro evaluation and molecular docking calculations.基于α-氨基酸的 2-氧代酰胺对分泌型磷脂酶 A₂的抑制作用：合成、体外评价和分子对接计算。

Bioorg Med Chem. 2011 Jan 15;19(2):735-43. doi: 10.1016/j.bmc.2010.12.030. Epub 2010 Dec 16.

Quantitative comparison of catalytic mechanisms and overall reactions in convergently evolved enzymes: implications for classification of enzyme function.收敛进化酶的催化机制和总反应的定量比较：对酶功能分类的启示。

PLoS Comput Biol. 2010 Mar 12;6(3):e1000700. doi: 10.1371/journal.pcbi.1000700.

Molecular basis of phospholipase A2 activity toward phospholipids with sn-1 substitutions.磷脂酶A2对具有sn-1取代的磷脂的活性的分子基础。

Biophys J. 2008 Jan 1;94(1):14-26. doi: 10.1529/biophysj.107.110106. Epub 2007 Sep 7.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验