Mohamed A H
J Oral Pathol. 1976 Mar;5(2):103-21. doi: 10.1111/j.1600-0714.1976.tb01871.x.
Tissues from four local recurrences of a palatal tumor and regional lymph node metastases were studied by light microscopy while ultrastructural observations were made on the most recent tumor. The tumor was composed of solid sheets, clumps, and small nests of polyhedral epithelial cells with well-defined cell boundaries, clear cytoplasm, and cellular pleomorphism. Histochemical stains indicated the presence of abundant intracellular glycogen deposits in all tumor specimens examined. Ultrastructural observations revealed solid sheets of epithelial cells which lacked both surrounding basement lamina and ductal arrangements. The cytoplasm of the tumor cells was filled with beta glycogen deposits and contained scattered bundles of tonofilaments and scant organelles. The transition between the glycogen-rich tumor cells and surface epithelium showed intervening cells which contained diffusely dispersed ribosomes and small amounts of glycogen. The tumor probably originated from surface epithelium.
对腭部肿瘤的四处局部复发组织及区域淋巴结转移组织进行了光学显微镜研究，同时对最新的肿瘤进行了超微结构观察。肿瘤由多面体上皮细胞的实性片层、团块和小巢组成，细胞边界清晰，细胞质透明，有细胞多形性。组织化学染色表明，在所有检查的肿瘤标本中均存在丰富的细胞内糖原沉积。超微结构观察显示上皮细胞的实性片层，既缺乏周围的基底膜，也没有导管排列。肿瘤细胞的细胞质充满β糖原沉积，含有散在的张力丝束和少量细胞器。富含糖原的肿瘤细胞与表面上皮之间的过渡显示，中间细胞含有分散的核糖体和少量糖原。该肿瘤可能起源于表面上皮。
