Lancman M E, Asconapé J J, Penry J K
Department of Neurology, Bowman Gray School of Medicine, Winston-Salem, North Carolina 27157.
Epilepsia. 1994 Mar-Apr;35(2):302-6. doi: 10.1111/j.1528-1157.1994.tb02434.x.
We reviewed records of 85 patients with juvenile myoclonic epilepsy (JME) for significant asymmetries in clinical seizures or the EEG. We noted asymmetries in 26 of 85 patients (30.6%). Only 2 patients had both clinical and EEG asymmetries; 12 had clinical asymmetries and 12 had EEG asymmetries exclusively. Analysis of patients with and without asymmetries showed no statistically significant differences in comparisons of sex, age at seizure onset, family history of epilepsy, seizure type, or response to treatment. The delay in diagnosis was greater in JME patients with asymmetries (9.5 years) than in JME patients with no asymmetries (7.5 years), but this difference was not statistically significant. Fourteen of the 26 patients with asymmetries (53.8%) were initially misdiagnosed as having partial seizures. Asymmetries in JME patients are not only common, but are also a frequent cause of misdiagnosis.
我们回顾了85例青少年肌阵挛性癫痫（JME）患者的记录，以查找临床发作或脑电图中的显著不对称情况。我们注意到85例患者中有26例（30.6%）存在不对称情况。只有2例患者临床和脑电图均存在不对称；12例仅有临床不对称，12例仅有脑电图不对称。对有和没有不对称情况的患者进行分析显示，在性别、癫痫发作起始年龄、癫痫家族史、发作类型或治疗反应的比较中，没有统计学上的显著差异。有不对称情况的JME患者诊断延迟（9.5年）比没有不对称情况的JME患者（7.5年）更长，但这种差异没有统计学意义。26例有不对称情况的患者中有14例（53.8%）最初被误诊为局灶性发作。JME患者的不对称情况不仅常见，而且也是误诊的常见原因。
