Seppälä B, Ainamo J
Department of Peridontology, University of Helsinki, Finland.
J Clin Periodontol. 1994 Mar;21(3):161-5. doi: 10.1111/j.1600-051x.1994.tb00297.x.
In the present site-by-site follow-up study, the change in amount of approximal alveolar bone was assessed after 1 year from the baseline examination in 38 and after 2 years in 22 dentate subjects all with insulin-dependent diabetes mellitus. The diabetics, aged 35 to 56 years at baseline, had a history of a mean duration of 18 years of insulin-dependent diabetes mellitus and were under medical treatment at the outpatient clinic of the III Department of Medicine, University Central Hospital of Helsinki as well as at 2 diabetic clinics of the Helsinki Health Centre. Based upon their long-term medical records, 26 subjects were after 1 year, and 16 subjects after 2 years from the baseline, identified as having poorly controlled insulin-dependent diabetes (PIDD). At the 1-year examination, 12 subjects were classified as having controlled insulin-dependent diabetes (CIDD) as compared to 6 subjects at the 2-year examination. After 1 and 2 years, from baseline, site-by-site measurements were recorded for plaque index scores, bleeding after probing, loss of attachment, and radiographic loss of alveolar bone. After 1 and 2 years from baseline, the PIDD subjects exhibited higher mean %s of sites with improved bleeding scores (P < 0.01, chi 2-test) than the CIDD subjects. At the 2-year examination, the mean % of sites with loss of approximal alveolar bone was greater in the PIDD than in the CIDD group (P < 0.05, chi 2-test). The greatest differences between PIDD and CIDD subjects were found when recordings for only canines were analyzed at the 1- and 2-year examinations (P < 0.05, chi 2-test). The results of our current 2-year longitudinal site-by-site examinations confirm earlier results that poorly controlled insulin-dependent diabetes mellitus is strongly related to the amount of alveolar bone loss.
在本次逐部位随访研究中，对38名胰岛素依赖型糖尿病患者在基线检查1年后以及22名患者在2年后的邻面牙槽骨量变化进行了评估。这些糖尿病患者在基线时年龄为35至56岁，胰岛素依赖型糖尿病平均病程为18年，在赫尔辛基大学中心医院医学三部门诊以及赫尔辛基健康中心的2个糖尿病诊所接受治疗。根据他们的长期医疗记录，在基线检查1年后有26名受试者，2年后有16名受试者被确定为胰岛素依赖型糖尿病控制不佳（PIDD）。在1年检查时，有12名受试者被归类为胰岛素依赖型糖尿病得到控制（CIDD），而在2年检查时为6名。从基线开始1年和2年后，记录了菌斑指数评分、探诊后出血、附着丧失和牙槽骨影像学丧失的逐部位测量值。从基线开始1年和2年后，PIDD受试者出血评分改善的部位平均百分比高于CIDD受试者（P<0.01，卡方检验）。在2年检查时，PIDD组邻面牙槽骨丧失部位的平均百分比高于CIDD组（P<0.05，卡方检验）。在1年和2年检查时，仅分析犬齿记录时发现PIDD和CIDD受试者之间差异最大（P<0.05，卡方检验）。我们目前2年纵向逐部位检查的结果证实了早期结果，即胰岛素依赖型糖尿病控制不佳与牙槽骨丧失量密切相关。
