Simon M A, Daniel M D, Lee-Parritz D, King N W, Ringler D J
Division of Comparative Pathology, Harvard Medical School, New England Regional Primate Research Center, Southborough, MA 01772-9102.
Lab Anim Sci. 1993 Dec;43(6):545-50.
A cynomolgus monkey (Macaca fascicularis) was euthanatized 1 week following dystocia because of severe peritonitis. Histologic examination revealed lesions characteristic of herpesvirus infection in lungs, liver, spleen, bone marrow, uterus, and adrenal gland, and on the serosal surface of intestines, pancreas, and reproductive tract. Immunohistochemical studies on liver and lungs revealed Herpes B-like antigens in the lesions. B virus was isolated from serum. As systemic B-virus infection was not diagnosed before death of the monkey, these findings underscore the need for universal precautions when handling blood, fluids, or tissues from macaques.
一只食蟹猴（猕猴）因难产导致严重腹膜炎，在产后1周实施了安乐死。组织学检查发现，在肺、肝、脾、骨髓、子宫和肾上腺以及肠道、胰腺和生殖道的浆膜表面有疱疹病毒感染的特征性病变。对肝脏和肺进行免疫组织化学研究，在病变中发现了B型疱疹样抗原。从血清中分离出了B病毒。由于在这只猴子死亡前未诊断出全身性B病毒感染，这些发现强调了在处理猕猴的血液、体液或组织时采取普遍预防措施的必要性。
