Kupferminc M J, Lee M J, Green D, Peaceman A M
Department of Obstetrics and Gynecology, Northwestern University Medical School, Chicago, Illinois.
Obstet Gynecol. 1994 May;83(5 Pt 2):806-7.
The antiphospholipid antibody syndrome has been associated with thromboembolic events, thrombocytopenia, fetal death, fetal growth retardation, and early-onset severe preeclampsia.
A postpartum woman developed fever, pulmonary infiltrates, cardiac conduction defects, and renal insufficiency following severe preeclampsia. She tested positive for lupus anticoagulant and anticardiolipin antibody, and responded to steroid therapy and plasmapheresis.
The postpartum multi-system involvement suggests that a variety of clinical presentations may be associated with antiphospholipid antibodies. Treatment with plasmapheresis or corticosteroids may be of value in similar cases.
抗磷脂抗体综合征与血栓栓塞事件、血小板减少症、胎儿死亡、胎儿生长受限及早发型重度子痫前期有关。
一名产后妇女在重度子痫前期后出现发热、肺部浸润、心脏传导缺陷及肾功能不全。她狼疮抗凝物及抗心磷脂抗体检测呈阳性，并对类固醇治疗及血浆置换有反应。
产后多系统受累提示多种临床表现可能与抗磷脂抗体有关。血浆置换或皮质类固醇治疗在类似病例中可能有价值。
