DeLaurier G A, Ivey R K, Johnson R H
Department of Surgery, Medical College of Georgia, Augusta 30912-4000.
Am J Surg. 1994 Mar;167(3):302-5. doi: 10.1016/0002-9610(94)90204-6.
Our previous canine research suggested that the determination of peritoneal fluid lactic acid levels may be helpful in the evaluation of potential acute abdomen cases. To investigate the clinical significance of those findings, we obtained simultaneous peritoneal and plasma lactic acid values from patients undergoing emergency celiotomy or in whom surgical consultation was sought to rule out an acute abdomen. The lactic acid value was significantly higher in peritoneal fluid than in plasma in patients who were found to have hollow viscus perforation, gangrenous intestine, peritonitis, or intra-abdominal abscess. In contrast, the values were similar in patients who did not have those conditions. Our findings suggest that the calculated difference between simultaneous peritoneal and plasma lactic acid values is a helpful diagnostic index for patients in whom the diagnosis of acute abdomen is not otherwise obvious.
我们之前的犬类研究表明，测定腹腔液乳酸水平可能有助于评估潜在的急腹症病例。为了研究这些发现的临床意义，我们获取了接受急诊剖腹手术患者或因排除急腹症而寻求手术会诊患者的同时期腹腔液和血浆乳酸值。在被发现有中空脏器穿孔、坏疽性肠病、腹膜炎或腹腔内脓肿的患者中，腹腔液中的乳酸值显著高于血浆中的乳酸值。相比之下，没有这些情况的患者中，两者的值相似。我们的研究结果表明，同时期腹腔液和血浆乳酸值的计算差值对急腹症诊断不明确的患者是一个有用的诊断指标。
