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[鼻咽部微生物——脑膜炎球菌的拮抗剂]

[Nasopharyngeal microorganisms--antagonists of meningococci].

作者信息

Bochkov I A

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1975 Nov(11):81-6.

PMID:816119
Abstract

A study was made of the species composition of symbiotic microbial flora of the nasopharynx in healthy persons and meningococcus carriers, inhibiting in vitro the growth of the test strains of miningococci. Saprophytic streptococci and particularly Str. salivarius served as the principal and the most active antagonists of meningococci in both groups of the persons examined. Comparison of the inhibitory activity of antagonists in the groups examined revealed no significant differences. However, there were seen differences in the quantitative composition of the isolated antagonists: saprophytic streptococci, particularly Str. salivarius were isolated in great amounts, and more frequently from healthy individuals, and nondifferentiated Gram positive cocci of conditionally distinguished group--from carriers. Taking into consideration the high inhibitory activity of Str. salivarius it is supposed that it can be used as an indicator of the state of insensitiveness of the human organism to the meningococcus infection.

摘要

对健康人和脑膜炎球菌携带者鼻咽部共生微生物菌群的物种组成进行了研究,这些菌群在体外抑制脑膜炎球菌测试菌株的生长。腐生链球菌,特别是唾液链球菌,是两组受检者中脑膜炎球菌的主要且最活跃的拮抗剂。对受检组中拮抗剂的抑制活性进行比较,未发现显著差异。然而,在分离出的拮抗剂的定量组成上存在差异:腐生链球菌,特别是唾液链球菌,大量分离得到,且更常见于健康个体,而条件区分组的未分化革兰氏阳性球菌——则来自携带者。考虑到唾液链球菌的高抑制活性,推测它可作为人体对脑膜炎球菌感染不敏感状态的指标。

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