[脑膜炎双球菌的拮抗和产细菌素活性]

[Antagonistic and bacteriocinogenic activity of Meningococci].

作者信息

Bochkov I A, Larina L I

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1978 Apr(4):107-10.

Abstract

Antagonistic and bacteriocinogenic activity was studied in 169 strains of meningococci of various serological groups and with different localization in the human organism at the time of isolation. Bacteriocinogenic activity was revealed in all the meningococcus strains (by delayed antagonism method), and, in addition, antagonistic activity was found in 100 strains. The inhibitory activity was the greatest in meningococci isolated from the cerebrospinal fluid. The data obtained suggest an important inhibitory activity of meningococci, along with their resistance to the antagonistic activity of the nasopharyngeal microorganisms, in the manifestation of pathogenic properties in them.

摘要

对169株不同血清群、分离时在人体不同部位定位的脑膜炎球菌的拮抗和产细菌素活性进行了研究。所有脑膜炎球菌菌株均显示出产细菌素活性（采用延迟拮抗法），此外，在100株菌株中发现了拮抗活性。从脑脊液中分离出的脑膜炎球菌的抑制活性最强。所获得的数据表明，脑膜炎球菌在表现致病特性时具有重要的抑制活性，同时它们对鼻咽部微生物的拮抗活性具有抗性。