替卡西林和羧苄西林对铜绿假单胞菌作用的体外比较评价。
Comparative in vitro evaluation of the effects of ticarcillin and carbenicillin upon Psuedomonas aeruginosa.
作者信息
Kalkani E, Marketos N
出版信息
Antimicrob Agents Chemother. 1976 Jan;9(1):89-90. doi: 10.1128/AAC.9.1.89.
Abstract
An in vitro comparison of the effects of ticarcillin and carbenicillin was performed upon 164 strains of Pseudomonas aeruginosa. The two drugs displayed nearly identical inhibitory activities: for each, about 82.5% of the strains were inhibited by doses of 256 mug/ml or less. A low bactericidal activity was also observed. Strains of P. aeruginosa that were highly resistant to carbenicillin were also resistant to ticarcillin.
摘要
对164株铜绿假单胞菌进行了替卡西林和羧苄西林效果的体外比较。这两种药物显示出几乎相同的抑制活性：对于每种药物，约82.5%的菌株在256微克/毫升或更低剂量下受到抑制。还观察到低杀菌活性。对羧苄西林高度耐药的铜绿假单胞菌菌株对替卡西林也耐药。
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