Shapiro M F, Park R E, Keesey J, Brook R H
Division of General Internal Medicine and Health Services Research, UCLA School of Medicine/GIM 90024.
Health Serv Res. 1994 Apr;29(1):95-112.
This study investigated how mortality differences between groups of municipal versus voluntary hospitals are affected by case-mix adjustment methods.
We sampled about 10,000 random admissions from administrative data for patients hospitalized with each of six conditions in hospitals in New York City during 1984-1987.
We developed logistic regression models adjusting for age and gender, for principal diagnosis, for "limited other diagnoses" (secondary diagnoses that were very unlikely to result from care received), for "full other diagnoses" (all secondary diagnoses irrespective of whether they might have been due to care received), for previous diagnoses, and for other variables.
For five of the six conditions, when the limited other diagnoses adjustment was used there was higher mortality in the municipal hospitals (p < .05), with 3.3 additional deaths/100 admissions for myocardial infarction, 1.2 for pneumonia, 8.3 for stroke, 2.8 for head trauma, and 0.8 for hip repair. However, when the full other diagnoses adjustment was used, differences remained significant only for stroke (4.3 additional deaths/100 admissions) and head trauma (1.3) (p < .05).
Estimates of mortality differences between New York City municipal and voluntary hospitals are substantially affected by which secondary diagnoses are used in case-mix adjustment. Judgments of quality should not be based on administrative data unless models can be developed that validly capture level of sickness at admission.
本研究调查了病例组合调整方法如何影响市立医院与志愿医院之间的死亡率差异。
我们从1984 - 1987年纽约市医院中因六种疾病之一住院患者的行政数据中随机抽取了约10,000例入院病例。
我们开发了逻辑回归模型,对年龄、性别、主要诊断、“有限的其他诊断”(极不可能由所接受治疗导致的次要诊断)、“全部其他诊断”(所有次要诊断,无论是否可能由所接受治疗引起)、既往诊断及其他变量进行调整。
对于六种疾病中的五种,在使用有限的其他诊断调整时,市立医院的死亡率更高(p < .05),心肌梗死每100例入院病例多死亡3.3例,肺炎多死亡1.2例,中风多死亡8.3例,头部外伤多死亡2.8例,髋关节修复多死亡0.8例。然而,在使用全部其他诊断调整时,差异仅在中风(每100例入院病例多死亡4.3例)和头部外伤(多死亡1.3例)时仍具有统计学意义(p < .05)。
纽约市立医院与志愿医院之间死亡率差异的估计受病例组合调整中所使用的次要诊断的显著影响。除非能够开发出有效反映入院时疾病严重程度的模型,否则不应基于行政数据进行质量判断。