Melamed Y, Barkai G, Frydman M
Maxillofacial Centre, Medical Corps, Israel Defence Forces, Tel-Hashomer.
J Oral Pathol Med. 1994 Feb;23(2):88-91. doi: 10.1111/j.1600-0714.1994.tb00263.x.
Familial occurrence of supernumerary teeth is reported in a father and his son. While the father had only one supernumerary tooth in the maxillary premolar region, his son had 8 unerupted supernumerary teeth. In addition, both patients had joint hypermobility and stretchable skin, typical of EDS syndrome type III. To the best of our knowledge, the association of supernumerary teeth with Ehlers-Danlos syndrome has never been previously reported. Single supernumerary teeth (SSNT) are most commonly found in the maxillary anterior region, whereas multiple supernumerary teeth prevail in the mandibular premolar region. We suggest that the aetiology of multiple supernumerary teeth may be different from that of single supernumerary teeth.
据报道，一名父亲和他的儿子都有额外牙的家族性发病情况。父亲在上颌前磨牙区只有一颗额外牙，而他的儿子有8颗未萌出的额外牙。此外，两名患者都有关节活动过度和皮肤可拉伸的症状，这是Ⅲ型埃勒斯-当洛综合征（EDS综合征）的典型症状。据我们所知，额外牙与埃勒斯-当洛综合征的关联此前从未有过报道。单颗额外牙（SSNT）最常见于上颌前部区域，而多颗额外牙则以下颌前磨牙区居多。我们认为，多颗额外牙的病因可能与单颗额外牙不同。
