Patrick G, Struve F A
Psychiatry Department, Louisiana State University School of Medicine, Shreveport 71130-3932.
Clin Electroencephalogr. 1994 Jan;25(1):1-7. doi: 10.1177/155005949402500104.
Based on preliminary data suggesting that polydrug abuser subjects may have delayed wave V BAER latencies, we contrasted BAER latency and amplitude measures between a group of polydrug users and six different comparison groups of subjects drawn from our laboratory files. A series of analyses showed that BAER latencies were, in fact, prolonged for psychiatric polydrug users as compared with groups of medically screened and unscreened normals not using drugs and normals using marijuana only. However, further analyses which compared polydrug abusers with nondrug users or marijuana-only users drawn from a psychiatric patient population failed to confirm these differences, thus suggesting that psychiatric status was more important than polydrug abuse in producing BAER alterations. Furthermore, subsidiary analyses using wave I latency as statistical covariate suggested that wave V latency prolongations could, under certain circumstances, be epiphenomena or reflections of earlier wave I alterations.
基于初步数据表明多药滥用者可能存在V波脑干听觉诱发电位（BAER）潜伏期延迟，我们对比了一组多药使用者与从我们实验室档案中抽取的六个不同对照组受试者的BAER潜伏期和波幅测量值。一系列分析表明，与未使用药物的医学筛查和未筛查的正常人群组以及仅使用大麻的正常人群组相比，精神病性多药使用者的BAER潜伏期实际上延长了。然而，进一步将多药滥用者与从精神病患者群体中抽取的非药物使用者或仅使用大麻的使用者进行比较的分析未能证实这些差异，因此表明在产生BAER改变方面，精神状态比多药滥用更重要。此外，使用I波潜伏期作为统计协变量的辅助分析表明，在某些情况下，V波潜伏期延长可能是早期I波改变的附带现象或反映。
