Peralta V, Cuesta M J, de Leon J
Psychiatric Unit Virgen del Camino Hospital, Pamplona, Spain.
Acta Psychiatr Scand. 1991 Oct;84(4):336-9. doi: 10.1111/j.1600-0447.1991.tb03156.x.
The relationship between premorbid personality and schizophrenic symptoms assessed by the Scales for the Assessment of Positive and Negative Symptoms was explored in 115 DSM-III-R schizophrenics. The frequencies of normal, schizoid-schizotypal and other DSM-III-R personality disorders were 44%, 39% and 17%. Affective flattening and alogia were significantly more frequently present and severe in the schizoid-schizotypal group than in the rest of the patients. There were no differences in positive symptoms. It is suggested that, in some cases, negative symptoms are merely the persistence or exacerbation of schizoid traits present prior to the emergence of schizophrenic symptoms. These results should be cautiously interpreted because the premorbid personality was diagnosed in a retrospective way and the negative symptoms were assessed cross-sectionally.
我们对115名符合《精神疾病诊断与统计手册》第三版修订本（DSM-III-R）标准的精神分裂症患者进行了研究，探讨病前人格与通过阳性和阴性症状评定量表评估的精神分裂症症状之间的关系。正常人格、分裂样-分裂型人格及其他DSM-III-R人格障碍的出现频率分别为44%、39%和17%。与其他患者相比，分裂样-分裂型人格障碍组情感平淡和言语贫乏更为常见且严重。阳性症状方面则无差异。研究表明，在某些情况下，阴性症状可能仅仅是精神分裂症症状出现之前就已存在的分裂样特质的持续或加重。这些结果应谨慎解读，因为病前人格是通过回顾性方式诊断的，且阴性症状是通过横断面评估的。
