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美国的输血相关艾滋病。

Transfusion-associated (T-A)-AIDS in the United States.

作者信息

Ward J W

机构信息

Division of HIV/AIDS, CDC/DHHS, Atlanta, GA.

出版信息

Dev Biol Stand. 1993;81:41-3.

PMID:8174818
Abstract

To the end of December 1991, 4,709 persons with transfusion-associated (T-A)-AIDS were reported to the Centers for Disease Control and Prevention (CDC) (2.3% of 206,392 adult AIDS cases). Since 1990, the rate of T-A-AIDS case reporting has remained relatively constant at 160-190 cases diagnosed per quarter year. In comparison with other adults with AIDS, those with T-A-AIDS were more likely to be diagnosed with Candida esophagitis and wasting syndrome. Adults with T-A-AIDS tend to be older at diagnosis (mean age 55 years vs. 35 years), white (69% vs. 54%), and female (38% vs. 10%) than other adults with AIDS. However, these demographic differences have decreased over time. The median observed incubation period for T-A-AIDS was 58 months (range 1-154 mo.). Younger adult transfusion recipients had longer incubation periods than older adults. The changing epidemiology of T-A-AIDS reflects, in large part, the effectiveness of prevention strategies.

摘要

到1991年12月底,据疾病控制与预防中心(CDC)报告,有4709例输血相关(T-A)艾滋病患者(占206392例成人艾滋病病例的2.3%)。自1990年以来,T-A艾滋病病例报告率一直相对稳定,每季度确诊160 - 190例。与其他成年艾滋病患者相比,T-A艾滋病患者更易被诊断出患有念珠菌性食管炎和消瘦综合征。与其他成年艾滋病患者相比,T-A艾滋病成年患者确诊时年龄往往更大(平均年龄55岁对35岁),多为白人(69%对54%),女性比例也更高(38%对10%)。然而,随着时间推移,这些人口统计学差异有所减小。T-A艾滋病的观察到的中位潜伏期为58个月(范围1 - 154个月)。较年轻的成年输血受者潜伏期比年长的成年受者更长。T-A艾滋病流行病学的变化在很大程度上反映了预防策略的有效性。

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