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环境氟化物对人体关键生化过程的影响。

Effect of environmental fluorides on key biochemical processes in humans.

作者信息

Kedryna T, Stachurska M B, Ignacak J, Gumińska M

机构信息

Department of General Biochemistry, Collegium Medicum Jagiellonian University, Kraków.

出版信息

Folia Med Cracov. 1993;34(1-4):49-57.

PMID:8175063
Abstract

Several biochemical parameters connected with energy metabolism were studied in the inhabitants living in the neighbourhood of the Aluminium Smelter and in inhabitants of Chorzów, one of the most polluted towns in the Upper Silesian Industrial Region, chronically exposed to environmental fluorides and other toxic compounds. In people exposed to environmental fluorides excessive excretion of fluorides in urine was noted. This effect was connected with a decrease in urine and erythrocyte magnesium concentrations. Among several biochemical parameters an increase in blood glucose and lactate levels were found, leading to a decrease in blood ATP level. Supplementation of magnesium salts in inhabitants of Skawina caused a normalization of urine magnesium concentration, blood glucose and lactate levels, and increased blood ATP level, but did not diminish fluoride excretion in urine.

摘要

对生活在铝冶炼厂附近的居民以及上西里西亚工业区污染最严重的城镇之一乔尔祖夫的居民进行了几项与能量代谢相关的生化参数研究,这些居民长期暴露于环境氟化物和其他有毒化合物中。在接触环境氟化物的人群中,发现尿中氟化物排泄过多。这种效应与尿和红细胞镁浓度的降低有关。在几个生化参数中,发现血糖和乳酸水平升高,导致血液ATP水平降低。在斯卡维纳居民中补充镁盐可使尿镁浓度、血糖和乳酸水平恢复正常,并提高血液ATP水平,但并未减少尿中氟化物的排泄。

相似文献

1
Effect of environmental fluorides on key biochemical processes in humans.环境氟化物对人体关键生化过程的影响。
Folia Med Cracov. 1993;34(1-4):49-57.
2
[Biochemical indicators of carbohydrate and energy metabolism in the Chorzów population after long-term exposure to industrial pollutants].[长期暴露于工业污染物后乔尔祖夫人群碳水化合物和能量代谢的生化指标]
Folia Med Cracov. 1991;32(1-2):95-102.
3
[Magnesium in the blood and urine of the population living in polluted environment of Chorzów].[乔尔祖夫污染环境地区居民血液和尿液中的镁]
Folia Med Cracov. 1991;32(1-2):89-94.
4
[Fluorides in urine of the population living in polluted environment].[生活在污染环境中的人群尿液中的氟化物]
Folia Med Cracov. 1991;32(1-2):83-8.
5
[Characteristics of the population of Chorzów living in polluted health-threatening environment].[生活在受污染且威胁健康环境中的乔尔祖夫人群的特征]
Folia Med Cracov. 1991;32(1-2):71-81.
6
[ATP, glucose and lactate levels in the blood of persons exposed to fluorides before and after preventive administration of magnesium salts].[预防性给予镁盐前后接触氟化物人群血液中的三磷酸腺苷、葡萄糖和乳酸水平]
Folia Med Cracov. 1985;26(1-2):93-7.
7
Biochemical changes in the blood of humans chronically exposed to fluorides.长期接触氟化物的人体血液中的生化变化。
Acta Med Pol. 1975;16(3):215-24.
8
[Inhibitory effect of environmental pollutants on erythrocyte membrane ATPase activity in humans].[环境污染物对人体红细胞膜ATP酶活性的抑制作用]
Folia Med Cracov. 1991;32(1-2):103-10.
9
[Exposure of Poznan inhabitants to fluorides. II. Fluorides in urine and hair of school children].[波兹南居民的氟暴露。II. 学童尿液和头发中的氟化物]
Rocz Panstw Zakl Hig. 1997;48(1):53-8.
10
[Red cell system and selected red cell enzymes in men occupationally exposed to mercury vapours].[职业性接触汞蒸气男性的红细胞系统及选定的红细胞酶]
Przegl Lek. 2006;63 Suppl 7:74-83.

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