Bal S, Hasan S S
Thoracic Surgical Unit Royal Cornwall Hospitals, Treliske, Truro, U.K.
Int Surg. 1993 Oct-Dec;78(4):324-7.
The results of thoracoscopic biopsy and talc pleurodesis in the management of malignant pleural effusions, is analysed. The study population consisted of 213 patients. Pre-operative cytology was positive in only 27% of patients; the diagnostic yield using thoracoscopic biopsy was 91.5%. (Sensitivity 99%; specificity 100%; positive predicted value 100%; negative predicted value 88%). Talc pleurodesis at thoracoscopy produced symptomatic improvement in 93% of patients. Post-operative complications occurred in 3.7% and there was a 2.3% mortality. Recurrent effusion was not a significant clinical problem. Thoracoscopy enhances the accuracy of diagnosis of pleural effusions; simultaneous talc pleurodesis has a high therapeutic success.
分析了胸腔镜活检及滑石粉胸膜固定术在恶性胸腔积液治疗中的结果。研究对象包括213例患者。术前细胞学检查仅27%的患者呈阳性；胸腔镜活检的诊断率为91.5%。（敏感性99%；特异性100%；阳性预测值100%；阴性预测值88%）。胸腔镜下滑石粉胸膜固定术使93%的患者症状改善。术后并发症发生率为3.7%，死亡率为2.3%。复发性胸腔积液并非严重的临床问题。胸腔镜检查提高了胸腔积液诊断的准确性；同时进行滑石粉胸膜固定术治疗成功率高。
