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[从各类临床材料中分离出的铜绿假单胞菌菌株的抗生素行为]

[Antibiotic behavior of Ps. aeruginosa strains isolated from various types of clinical material].

作者信息

Savitskaia K I, Levina E N, Akatova N S

出版信息

Antibiotiki. 1981 Mar;26(3):99-105.

PMID:6786210
Abstract

Altogether 158 strains of P. aeruginosa isolated from the material of open and close cavities and blood of patients with bronchopulmonary diseases were studied. It was found that the majority of the virulent (92.6 per cent) and avirulent (70.3 per cent) cultures were characterized by multiple resistance to tetracycline, streptomycin, monomycin, kanamycin, levomycetin and polymyxin B with preserved sensitivity to gentamicin and carbenicillin. The source of the P. aeruginosa isolation had a significant influence on its relation to the effect of antibiotics: the highest number of the resistant cultures was isolated from the blood. No differences in the antibiotic effect on P. aeruginosa depending on the serotype were observed. No differences in the antibiotic effect on P. aeruginosa depending on the serotype were observed. Virulent cultures of P. aeruginosa typed with group agglutinating sera and isolated from the material of the open and close cavities were characterized by a higher resistance level to tetracycline, kanamycin, monomycin and levomycetin than the virulent not-typed strains.

摘要

共研究了从支气管肺疾病患者的开放和封闭腔道材料及血液中分离出的158株铜绿假单胞菌。结果发现,大多数强毒株(92.6%)和无毒株(70.3%)的培养物对四环素、链霉素、单霉素、卡那霉素、氯霉素和多粘菌素B具有多重耐药性,但对庆大霉素和羧苄青霉素仍敏感。铜绿假单胞菌的分离来源对其与抗生素效果的关系有显著影响:耐药培养物数量最多的是从血液中分离出来的。未观察到抗生素对铜绿假单胞菌的作用因血清型而异。用分组凝集血清分型并从开放和封闭腔道材料中分离出的铜绿假单胞菌强毒株,对四环素、卡那霉素、单霉素和氯霉素的耐药水平高于未分型的强毒株。

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