Brandau W
Klinik und Poliklinik für Nuklearmedizin, Westfälische Wilhelms-Universität, Münster, FRG.
Nuklearmedizin. 1994 Apr;33(2):118-24.
For the first time the revision of the "Guideline for radiation protection in medicine" defines extensive quality control procedures for radiopharmaceuticals. The principles of the 99Mo/99mTc-generator, the preparation of 99mTc-radiopharmaceuticals and the origin of the most frequent radiochemical impurities are illustrated. An introduction into the theory of thin layer chromatography is combined with a listing of radiochromatographic systems. This enables the determination of the radiochemical purity of the most important radiopharmaceuticals in clinical routine.
《医学辐射防护指南》的修订首次明确了针对放射性药物的广泛质量控制程序。阐述了99Mo/99mTc发生器的原理、99mTc放射性药物的制备以及最常见放射化学杂质的来源。薄层色谱理论的介绍与放射色谱系统列表相结合。这使得在临床常规中能够测定最重要放射性药物的放射化学纯度。
