Keshavan M S, Reynolds C F, Montrose D, Miewald J, Downs C, Sabo E M
University of Pittsburgh Medical School, Western Psychiatric Institute and Clinic, Pennsylvania 15213.
Acta Psychiatr Scand. 1994 Feb;89(2):122-5. doi: 10.1111/j.1600-0447.1994.tb01498.x.
The purpose of the study was to determine whether polysomnographic rapid eye movement (REM) sleep parameters distinguish between psychotic patients with and without a history of suicidal behavior. We examined both hand-scored and automated measures of rapid eye movement (REM) sleep in psychotic patients with and without a history of suicidal ideation or attempts. Patients with suicidal behavior had significantly increased REM activity and time both in the whole night data and in the first REM period. These findings suggest an association between REM sleep abnormalities and suicidal behavior, perhaps related to alteration in serotonergic function.
该研究的目的是确定多导睡眠图快速眼动（REM）睡眠参数是否能区分有和没有自杀行为史的精神病患者。我们检查了有和没有自杀意念或自杀未遂史的精神病患者的快速眼动（REM）睡眠的人工评分和自动测量指标。有自杀行为的患者在整晚数据以及第一个REM期的REM活动和时间均显著增加。这些发现表明REM睡眠异常与自杀行为之间存在关联，可能与血清素能功能改变有关。
