Leo P J, Cooper C, Songco C
Mount Sinai School of Medicine Integrated Residency in Emergency Medicine, New York.
Am J Emerg Med. 1994 May;12(3):358-63. doi: 10.1016/0735-6757(94)90161-9.
Hemolytic uremic syndrome (HUS), the most common cause of acute renal failure in childhood, has the potential to progress to a life-threatening illness. Its incidence in North America is increasing. Several studies have shown that Escherichia coli O157:H7 is associated with HUS. Although this pathogen was first recognized more than 10 years ago and is relatively common, many physicians are not aware of this diagnosis let alone the spectrum of illness associated with the bacteria. This case exemplifies what appears initially as gastroenteritis but, ultimately, becomes the final diagnosis of HUS. A case is presented to provide additional education to ensure the E coli O157:H7 infection is considered in the differential diagnosis of persons who present with bloody diarrhea.
溶血性尿毒症综合征(HUS)是儿童急性肾衰竭最常见的病因,有可能发展为危及生命的疾病。其在北美的发病率正在上升。多项研究表明,大肠杆菌O157:H7与HUS有关。尽管这种病原体在10多年前就首次被发现且相对常见,但许多医生并不了解这种诊断,更不用说与该细菌相关的疾病谱了。本病例最初看似是肠胃炎,但最终确诊为HUS。现呈现一个病例以提供更多知识,确保在对出现血性腹泻的患者进行鉴别诊断时考虑到大肠杆菌O157:H7感染。