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从猪身上分离出的沙门氏菌中β-内酰胺抗生素耐药性与镉之间的关系。

Relation between resistance to beta-lactam antibiotics and cadmium in salmonellae isolated from pigs.

作者信息

Hustavová H, Vozárová K, Havraneková D, Jacková S

机构信息

Institute of Preventive and Clinical Medicine, Bratislava.

出版信息

Folia Microbiol (Praha). 1994;39(1):74-8. doi: 10.1007/BF02814535.

Abstract

Of 50 Salmonella species isolated from pigs, 30 were resistant to cadmium and 18 of these also to azlocillin. The azlocillin-resistant isolates were resistant to cadmium at 80-500 mg/L CdSO4. A broader spectrum of resistance to azlocillin, ampicillin and cephazolin was found in strains resistant to < 200 mg/L CdSO4. Resistance to silver, mercury, chloramphenicol and streptomycin was independent of the resistance to beta-lactam antibiotics and Cd2+. Production and levels of beta-lactamase do not correlate with the spectrum of resistance.

摘要

从猪身上分离出的50种沙门氏菌中,30种对镉具有抗性,其中18种对阿洛西林也有抗性。对阿洛西林耐药的分离株在80 - 500 mg/L硫酸镉浓度下对镉具有抗性。在对<200 mg/L硫酸镉耐药的菌株中,发现了对阿洛西林、氨苄西林和头孢唑林更广泛的耐药谱。对银、汞、氯霉素和链霉素的耐药性与对β-内酰胺类抗生素和镉离子的耐药性无关。β-内酰胺酶的产生和水平与耐药谱无关。

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