Zhang X F, Miyano K, Nakazawa M, Tanifuji Y, Amaki Y
Department of Anesthesiology, Jikei University School of Medicine, Tokyo.
Masui. 1994 Mar;43(3):378-82.
The differential reactivities of three kinds of carbon dioxide absorbents, Soda lime, Soda lime A, and Baralyme with sevoflurane were investigated. Sevoflurane was made to react with each carbon dioxide absorbents in a glass vial or in a closed system under administration of carbon dioxide. Glass vials were kept at 55 degrees C and 70 degrees C, and three kinds of carbon dioxide absorbents were compared regarding their reactivity under each temperature. In a closed system, we also monitored the temperature of glass container which was filled with each carbon dioxide absorbent. In a glass vial, the highest reactivity of sevoflurane was found with Baralyme. Although Soda lime A decomposed sevoflurane less than Baralyme or Soda lime in glass vial, the highest reactivity of sevoflurane in a closed system was found with Soda lime A. On the other hand, Soda lime A increased the temperature of glass container most. As increasing temperature tends to promote reaction, the possibility that the high temperature of the glass container contributes to the reactivity of sevoflurane with carbon dioxide absorbents exists. These results suggest that the highest reactivity of Soda lime A with sevoflurane was caused by the highest temperature of glass container although its chemical composition makes it most reactive with sevoflurane than the others.
研究了三种二氧化碳吸收剂——碱石灰、碱石灰A和钡石灰与七氟醚的反应活性差异。在玻璃小瓶中或在通入二氧化碳的封闭系统中，使七氟醚与每种二氧化碳吸收剂发生反应。将玻璃小瓶保持在55摄氏度和70摄氏度，并比较三种二氧化碳吸收剂在每个温度下的反应活性。在封闭系统中，我们还监测了装有每种二氧化碳吸收剂的玻璃容器的温度。在玻璃小瓶中，七氟醚与钡石灰的反应活性最高。尽管在玻璃小瓶中，碱石灰A对七氟醚的分解少于钡石灰或碱石灰，但在封闭系统中，七氟醚与碱石灰A的反应活性最高。另一方面，碱石灰A使玻璃容器的温度升高最多。由于温度升高往往会促进反应，玻璃容器的高温导致七氟醚与二氧化碳吸收剂反应活性升高的可能性存在。这些结果表明，碱石灰A与七氟醚的最高反应活性是由玻璃容器的最高温度引起的，尽管其化学成分使其比其他物质与七氟醚的反应活性更高。
