Barlet E M, Penney L L
Department of Obstetrics and Gynecology, University of Missouri-Columbia Health Sciences Center.
Mo Med. 1994 Feb;91(2):85-8.
Therapeutic donor insemination is used in the treatment of male factor infertility with the use of cryopreserved semen being the standard of care. We reviewed the therapeutic donor insemination (TDI) program at the University of Missouri. Data from TDI cycles between January, 1985 and October 1988, using fresh semen, were retrospectively reviewed and compared to cycles using frozen semen between November, 1988 and April, 1991. Pregnancy rates were 60% and 49% for fresh and frozen cycles respectively with monthly fecundabilities of 0.10 and 0.086 respectively. These rates are comparable to those achieved in other centers. Additionally, as found in most other TDI programs, analysis reveals no statistically significant difference in fecundability with the use of a fresh specimen over frozen semen.
治疗性供精人工授精用于治疗男性因素不育症，使用冷冻精液是标准治疗方法。我们回顾了密苏里大学的治疗性供精人工授精（TDI）项目。对1985年1月至1988年10月使用新鲜精液的TDI周期数据进行回顾性分析，并与1988年11月至1991年4月使用冷冻精液的周期进行比较。新鲜精液周期和冷冻精液周期的妊娠率分别为60%和49%，每月受孕率分别为0.10和0.086。这些比率与其他中心的比率相当。此外，正如在大多数其他TDI项目中所发现的，分析显示使用新鲜精液与冷冻精液相比，受孕率没有统计学上的显著差异。
