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一例以不孕为表现的单纯促甲状腺激素缺乏症病例。

A case of isolated TSH deficiency presenting as infertility.

作者信息

Balen A H, Manning P J

机构信息

Department of Endocrinology, Cobbold Laboratories, Middlesex Hospital, London, UK.

出版信息

Postgrad Med J. 1994 Mar;70(821):225-7. doi: 10.1136/pgmj.70.821.225.

DOI:10.1136/pgmj.70.821.225
PMID:8183759
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2397864/
Abstract

We report a case of late-onset isolated thyroid stimulating hormone deficiency in a woman who presented with oligomenorrhoea and secondary hyperprolactinaemia. Hypothalamic and pituitary radiology and function was otherwise normal. The underlying aetiology of this condition is thought to be due to an inborn defect in the thyrotroph and treatment is with standard thyroid replacement therapy.

摘要

我们报告一例迟发性孤立性促甲状腺激素缺乏症的女性病例,该患者表现为月经过少和继发性高催乳素血症。下丘脑和垂体的放射学检查及功能均正常。这种情况的潜在病因被认为是促甲状腺细胞的先天性缺陷,治疗采用标准的甲状腺替代疗法。

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A case of isolated TSH deficiency presenting as infertility.一例以不孕为表现的单纯促甲状腺激素缺乏症病例。
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引用本文的文献

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Isolated TSH deficiency with a partially empty sella.孤立性促甲状腺激素缺乏伴部分空蝶鞍。
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本文引用的文献

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Familial growth retardation with isolated thyroid-stimulating hormone deficiency.
Clin Pediatr (Phila). 1984 Dec;23(12):675-8. doi: 10.1177/000992288402301202.
2
Hypothalamic hypothyroidism due to isolated thyrotropin-releasing hormone (TRH) deficiency.由于孤立性促甲状腺激素释放激素(TRH)缺乏导致的下丘脑性甲状腺功能减退症。
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Prolactin stimulation by thyrotropin-releasing hormone in a patient with isolated thyrotropin deficiency.促甲状腺激素释放激素对一名孤立性促甲状腺激素缺乏患者催乳素的刺激作用。
N Engl J Med. 1972 Nov 9;287(19):972-3. doi: 10.1056/NEJM197211092871909.
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Familial isolated thyrotropin deficiency with cretinism.伴有呆小症的家族性孤立性促甲状腺激素缺乏症。
N Engl J Med. 1971 Nov 4;285(19):1043-8. doi: 10.1056/NEJM197111042851902.
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Thyroid autoregulation: impact on thyroid structure and function in rats.
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Primary idiopathic hypothalamic hypothyroidism. Report of four cases.原发性特发性下丘脑性甲状腺功能减退症。4例报告。
Am J Med. 1987 Jul;83(1):171-4. doi: 10.1016/0002-9343(87)90515-8.
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Thyroid-stimulating hormone (TSH) deficiency caused by a single base substitution in the CAGYC region of the beta-subunit.由β亚基CAGYC区域中的单个碱基替换引起的促甲状腺激素(TSH)缺乏。
EMBO J. 1989 Aug;8(8):2291-6. doi: 10.1002/j.1460-2075.1989.tb08355.x.
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Serum free thyrotropin subunit in congenital isolated thyrotropin deficiency.先天性孤立性促甲状腺激素缺乏症中的血清游离促甲状腺激素亚基
Endocrinol Jpn. 1988 Jun;35(3):517-21. doi: 10.1507/endocrj1954.35.517.
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Rapid detection of a point mutation in thyroid-stimulating hormone beta-subunit gene causing congenital isolated thyroid-stimulating hormone deficiency.
Jinrui Idengaku Zasshi. 1991 Dec;36(4):313-6. doi: 10.1007/BF01883604.
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[The thyroid gland of the newborn infant and postnatal iodine overload].[新生儿的甲状腺及出生后碘过载]
Arch Fr Pediatr. 1979 Apr;36(4):356-68.