Upadhyay S S, Saji M J, Sell P, Sell B, Yau A C
Duchess of Kent Children's Hospital, Hong Kong.
Spine (Phila Pa 1976). 1994 Mar 1;19(5):542-9. doi: 10.1097/00007632-199403000-00009.
Of 112 patients who entered the Medical Research Council's prospective study on the surgical management of spinal tuberculosis, 105 were available for review at a mean follow-up of 15.3 years postoperatively. All these patients were age 18 years or more at the time of surgery. Seventy-one patients had radical surgery; the remaining 34 underwent debridement surgery. The longitudinal changes in spinal deformity were evaluated using kyphus and deformity angles from lateral spinal radiographs obtained at preoperative evaluation, postoperatively at 6 months, 1 year, and 5 years, and at final follow-up. The mean kyphos and deformity angles showed correction after radical surgery at 6 months' evaluation; thereafter there were minimal variations up to final follow-up. Those who underwent debridement surgery showed an increase in these angles at 6 months postoperative evaluation; thereafter there were practically no changes in thoracic and thoracolumbar tuberculosis, whereas in lumbar tuberculosis there was spontaneous correction from 1 year post-surgery onward. The changes in mean kyphos and deformity angles at 6 months postoperative evaluation from their preoperative values were significantly different between the two surgical groups, where radical surgery produced better correction. Thus, the choice of surgery--radical or debridement--is important in determining the fate of spinal deformity in the management of tuberculosis of the spine.
在参加医学研究委员会脊柱结核手术治疗前瞻性研究的112例患者中,105例在术后平均15.3年时接受了复查。所有这些患者手术时年龄均在18岁及以上。71例患者接受了根治性手术;其余34例接受了清创手术。利用术前评估、术后6个月、1年、5年及最终随访时获得的脊柱侧位X线片上的后凸角和畸形角评估脊柱畸形的纵向变化。根治性手术后6个月评估时,平均后凸角和畸形角显示得到矫正;此后直至最终随访,变化极小。接受清创手术的患者术后6个月评估时这些角度增大;此后,胸椎和胸腰椎结核患者几乎没有变化,而腰椎结核患者术后1年起出现自发矫正。术后6个月评估时,两个手术组的平均后凸角和畸形角相对于术前值的变化存在显著差异,根治性手术矫正效果更好。因此,在脊柱结核的治疗中,选择根治性手术还是清创手术对于决定脊柱畸形的转归很重要。