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儿童脊柱结核手术治疗的17年前瞻性研究。香港手术与清创手术治疗畸形的短期和长期结果比较。

17-year prospective study of surgical management of spinal tuberculosis in children. Hong Kong operation compared with debridement surgery for short- and long-term outcome of deformity.

作者信息

Upadhyay S S, Sell P, Saji M J, Sell B, Yau A C, Leong J C

机构信息

Department of Orthopaedic Surgery, Duchess of Kent Children's Hospital, Hong Kong.

出版信息

Spine (Phila Pa 1976). 1993 Sep 15;18(12):1704-11. doi: 10.1097/00007632-199309000-00020.

DOI:10.1097/00007632-199309000-00020
PMID:8235852
Abstract

A comparative analysis of the short and long-term results of two surgical procedures, radical excision or debridement, for the management of spinal tuberculosis in children is reported. Eighty children (47 treated with radical surgery and 33 with debridement) were prospectively studied and followed to maturity (mean follow-up, 17 years postoperatively). The kyphus and deformity angles were measured from lateral spinal radiographs using an electronic digitizer. The results can be summarized as follows: 1) Long-term clinical outcome of the two surgical procedures were equally good for recovery of neurologic deficit and relief of pain. There was no incidence of reactivation and/or recurrence of tuberculous lesion in either group; 2) The mean changes in kyphus and deformity angles at the 6-month postoperative evaluation compared to their preoperative value were significantly different for the two surgical groups. There was an overall correction in these angles after radical surgery, whereas there was a deterioration after debridement surgery; 3) There were no significant differences in the changes in kyphus or deformity angles at final follow-up from their 6-month postoperative measurements between the two surgical groups; 4) The majority of children (56%) showed an improvement in deformity angle of 5 degrees or more after radical surgery at the 6-month postoperative evaluation, whereas 69% of children showed deterioration after debridement surgery; 5) At final follow-up in lumbar tuberculosis, 60% of patients in the debridement group had 10 degrees or more kyphus angle, whereas only one patient in the radical group had a kyphotic lumbar spine due to graft failure.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

本文报告了对两种手术方法(根治性切除或清创术)治疗儿童脊柱结核的短期和长期结果的比较分析。对80名儿童(47例行根治性手术,33例行清创术)进行了前瞻性研究,并随访至成年(术后平均随访17年)。使用电子数字化仪从脊柱侧位X线片测量后凸角和畸形角。结果总结如下:1)两种手术方法在神经功能缺损恢复和疼痛缓解方面的长期临床效果同样良好。两组均无结核病灶再激活和/或复发的情况;2)术后6个月评估时,与术前值相比,两种手术组的后凸角和畸形角平均变化有显著差异。根治性手术后这些角度总体得到矫正,而清创术后则恶化;3)两组在最终随访时,后凸角或畸形角相对于术后6个月测量值的变化无显著差异;4)大多数儿童(56%)在根治性手术后6个月评估时畸形角改善5度或更多,而69%的儿童在清创术后畸形角恶化;5)在腰椎结核的最终随访中,清创组60%的患者后凸角为10度或更大,而根治组只有1例患者因植骨失败出现腰椎后凸。(摘要截取自250字)

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