一般人群人体组织中的氯代二噁英和二苯并呋喃：选择性综述。
Chlorinated dioxins and dibenzofurans in human tissue from general populations: a selective review.
作者信息
Schecter A, Fürst P, Fürst C, Päpke O, Ball M, Ryan J J, Hoang D C, Le C D, Hoang T Q, Cuong H Q
机构信息
Department of Preventive Medicine, College of Medicine, State University of New York-Health Science Center/Syracuse, Binghamton 13903.
出版信息
Environ Health Perspect. 1994 Jan;102 Suppl 1(Suppl 1):159-71. doi: 10.1289/ehp.94102s1159.
Abstract
During the past decade a considerable amount of data has been generated concerning polychlorinated dibenzodioxin (PCDD) and polychlorinated dibenzofuran (PCDF) levels in humans from many geographical locations. To organize these data in a useful fashion for environmental purposes and for consideration of human toxicity, selected portions of our data are presented in a somewhat atypical fashion, by percentage contribution of individual congeners to total PCDD/Fs in human tissue, and to the total dioxin equivalents (TEq). This is done to better characterize congener contributions from environmental contamination in various geographical regions at this time and health-related levels. To present the findings in a global perspective, data from widely different locations are presented including the United States, Germany, Vietnam, the former Soviet Union, Thailand, Cambodia, China, South Africa, and Guam.
摘要
在过去十年中，已经产生了大量关于来自许多地理位置的人体中多氯二苯并二恶英（PCDD）和多氯二苯并呋喃（PCDF）水平的数据。为了以一种有用的方式整理这些数据，以用于环境目的和考虑人体毒性，我们的数据的选定部分以一种有点非典型的方式呈现，即按各个同系物对人体组织中总PCDD/Fs以及对总二恶英当量（TEq）的贡献百分比来呈现。这样做是为了更好地描述目前不同地理区域环境污染物的同系物贡献以及与健康相关的水平。为了从全球角度呈现这些发现，展示了来自广泛不同地点的数据，包括美国、德国、越南、前苏联、泰国、柬埔寨、中国、南非和关岛。
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本文引用的文献
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Science. 1984 Nov 2;226(4674):568-9. doi: 10.1126/science.226.4674.568.
2
An analytical method for detecting TCDD (dioxin): levels of TCDD in samples from Vietnam.一种检测2,3,7,8-四氯二苯并对二恶英（二恶英）的分析方法：越南样本中2,3,7,8-四氯二苯并对二恶英的含量
Environ Health Perspect. 1973 Sep;5:27-35. doi: 10.1289/ehp.730527.
3
Calculation of 2,3,7,8-TCDD equivalent concentrations of complex environmental contaminant mixtures.复杂环境污染物混合物中2,3,7,8-四氯二苯并对二恶英等效浓度的计算。
Environ Health Perspect. 1986 Dec;70:221-7. doi: 10.1289/ehp.8670221.
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Dioxin-like effects observed in male rats following exposure to octachlorodibenzo-p-dioxin (OCDD) during a 13-week study.在一项为期13周的研究中，雄性大鼠暴露于八氯二苯并对二恶英（OCDD）后出现了类二恶英效应。
Toxicol Appl Pharmacol. 1988 Mar 30;93(1):31-46. doi: 10.1016/0041-008x(88)90023-3.
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Toxicol Appl Pharmacol. 1988 Mar 30;93(1):22-30. doi: 10.1016/0041-008x(88)90022-1.
6
Dioxins and dibenzofurans in blood and adipose tissue of Agent Orange-exposed Vietnam veterans and matched controls.
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7
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