Margolin B H, Kim B S, Smith M G, Fetterman B A, Piegorsch W W, Zeiger E
Department of Biostatistics, School of Public Health, University of North Carolina at Chapel Hill 27599-7400.
Environ Health Perspect. 1994 Jan;102 Suppl 1(Suppl 1):91-4. doi: 10.1289/ehp.94102s191.
In this article, the measurement of the potency of a chemical or mixture from its dose response in a particular assay is addressed. Attention is focused on data from the Ames Salmonella assay. Three measures of potency are explored and shown to be highly correlated. The presentation then discusses specific areas of research that might benefit from a study of potency.
在本文中,探讨了根据特定试验中的剂量反应来测定化学物质或混合物的效力。重点关注艾姆斯沙门氏菌试验的数据。研究了三种效力测量方法,并表明它们高度相关。随后的论述讨论了可能从效力研究中受益的具体研究领域。