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Effect of antimicrobial and antineoplastic drugs on the uptake of fluconazole by human neutrophils and tissue culture cells.

作者信息

García I, Pascual A, Conejo C, Salvador J, Perea E J

机构信息

Department of Microbiology, University of Seville School of Medicine, Spain.

出版信息

Eur J Clin Microbiol Infect Dis. 1993 Dec;12(12):944-7. doi: 10.1007/BF01992170.

DOI:10.1007/BF01992170
PMID:8187791
Abstract

The effect of eight antimicrobial and three antineoplastic drugs on the uptake of fluconazole by human neutrophils and culture epithelial cells was evaluated. Fluconazole reached higher concentrations intracellularly than extracellularly (cellular to extracellular concentration ratio C/E > or = 1.3) in the presence of therapeutical concentrations of the antimicrobial and antineoplastic agents evaluated.

摘要

相似文献

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本文引用的文献

1
Uptake and intracellular activity of fluconazole in human polymorphonuclear leukocytes.氟康唑在人多形核白细胞中的摄取及细胞内活性
Antimicrob Agents Chemother. 1993 Feb;37(2):187-90. doi: 10.1128/AAC.37.2.187.
2
Bacteremias and fungemias in oncologic patients with central venous catheters: changing spectrum of infection.患有中心静脉导管的肿瘤患者的菌血症和真菌血症：感染谱的变化
Arch Intern Med. 1982 Aug;142(8):1456-9.
3
Infectious complications in leukemic patients.白血病患者的感染并发症。
Semin Hematol. 1982 Jul;19(3):193-226.
4
Effects of antimicrobial and antineoplastic drugs on the phagocytic and microbicidal function of the polymorphonuclear leukocyte.抗菌和抗肿瘤药物对多形核白细胞吞噬及杀菌功能的影响。
Rev Infect Dis. 1982 May-Jun;4(3):683-97. doi: 10.1093/clinids/4.3.683.
5
Quantitative relationships between circulating leukocytes and infection in patients with acute leukemia.急性白血病患者循环白细胞与感染之间的定量关系。
Ann Intern Med. 1966 Feb;64(2):328-40. doi: 10.7326/0003-4819-64-2-328.
6
Activity of fluconazole (UK 49,858) and ketoconazole against Candida albicans in vitro and in vivo.氟康唑（UK 49,858）和酮康唑在体外及体内对白色念珠菌的活性。
Antimicrob Agents Chemother. 1986 Sep;30(3):418-22. doi: 10.1128/AAC.30.3.418.
7
Fluorometric measurement of ofloxacin uptake by human polymorphonuclear leukocytes.人多形核白细胞摄取氧氟沙星的荧光测定法
Antimicrob Agents Chemother. 1989 May;33(5):653-6. doi: 10.1128/AAC.33.5.653.
8
Effect of antimicrobial and antineoplastic drugs alone and in combination on the phagocytic and candidacidal function of human polymorphonuclear leucocytes.抗菌药物和抗肿瘤药物单独及联合使用对人多形核白细胞吞噬和杀念珠菌功能的影响。
J Antimicrob Chemother. 1989 Jan;23(1):87-94. doi: 10.1093/jac/23.1.87.
9
Effect of methotrexate alone and in combination with antifungal drugs on the growth of Candida albicans.甲氨蝶呤单独及与抗真菌药物联合使用对白色念珠菌生长的影响。
J Antimicrob Chemother. 1989 Jun;23(6):837-47. doi: 10.1093/jac/23.6.837.
10
Drug interactions with fluconazole.氟康唑的药物相互作用。
Rev Infect Dis. 1990 Mar-Apr;12 Suppl 3:S327-33. doi: 10.1093/clinids/12.supplement_3.s327.