Inoue Y, Igase M, Otsuka T, Yokoyama A, Kohno N, Hiwada K
Second Department of Internal Medicine, Ehime University School of Medicine, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1994 Mar;32(3):288-92.
A 60-year-old obese woman was admitted for evaluation of excessive daytime sleepiness, loud snoring, cyanosis, systemic edema, hypertension and diabetes mellitus. Laboratory examination showed severe hypoxemia, hypercapnea, metabolic alkalosis, hypokalemia and hyperaldosteronism. CT scan showed a left adrenal tumor. A diagnosis of obstructive sleep apnea syndrome associated with primary aldosteronism was established. Metabolic alkalosis, hypokalemia and sodium retention due to hyperaldosteronism were thought to be factors exacerbating her sleep apnea.
一名60岁肥胖女性因白天过度嗜睡、大声打鼾、发绀、全身性水肿、高血压和糖尿病入院评估。实验室检查显示严重低氧血症、高碳酸血症、代谢性碱中毒、低钾血症和醛固酮增多症。CT扫描显示左肾上腺肿瘤。诊断为阻塞性睡眠呼吸暂停综合征合并原发性醛固酮增多症。醛固酮增多症导致的代谢性碱中毒、低钾血症和钠潴留被认为是加重其睡眠呼吸暂停的因素。
