Glautier S, Drummond D C
Addiction Research Unit, National Addiction Centre, London, England.
J Stud Alcohol. 1994 Mar;55(2):224-9. doi: 10.15288/jsa.1994.55.224.
A group of 35 severely dependent male alcoholic patients undergoing cue exposure treatment were studied. Thirty-one subjects had complete data and their physiological and subjective responses to drink cues on the first day of the cue exposure program were subjected to a principal components analysis. The principal component loadings were then used to construct a single measure of responsivity and this responsivity measure was found to correlate significantly with Severity of Alcohol Dependence Questionnaire (SADQ) scores. Further analysis of the relationship between responsivity and the subscales of the SADQ showed that the experience of affective withdrawal symptoms, craving for alcohol and drinking to relieve withdrawal symptoms were the most strongly correlated with responsivity.
对一组35名接受线索暴露治疗的严重依赖酒精的男性患者进行了研究。31名受试者有完整的数据,他们在线索暴露计划第一天对饮酒线索的生理和主观反应进行了主成分分析。然后,主成分负荷被用来构建一个反应性的单一测量指标,发现这个反应性测量指标与酒精依赖严重程度问卷(SADQ)得分显著相关。对反应性与SADQ子量表之间关系的进一步分析表明,情感戒断症状的体验、对酒精的渴望以及为缓解戒断症状而饮酒与反应性的相关性最强。