亨廷顿舞蹈病的脑电图功率谱：临床与神经心理学关联
EEG power spectra in Huntington's disease: clinical and neuropsychological correlates.
作者信息
Bylsma F W, Peyser C E, Folstein S E, Folstein M F, Ross C, Brandt J
机构信息
Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287-7218.
出版信息
Neuropsychologia. 1994 Feb;32(2):137-50. doi: 10.1016/0028-3932(94)90001-9.
Quantitative power spectral analysis (PSA) was applied to frontal (F3, F4, F7, F8), temporal (T5, T6), and occipital (O1, O2) EEGs of 16 Huntington's disease (HD) patients and eight healthy control subjects. PSA revealed HD patients' EEGs to be abnormal: (i) raw and percent Alpha power were reduced; (ii) raw and percent Theta power were reduced at F3 and F4; (iii) percent Delta and percent Beta power were increased; (iii) Theta frequency was reduced by approximately 1.0 Hz. Frontal and temporal EEG power measures and decreased EEG amplitude correlated with severity of neurological and cognitive impairment.
对16名亨廷顿舞蹈症（HD）患者和8名健康对照者的额叶（F3、F4、F7、F8）、颞叶（T5、T6）和枕叶（O1、O2）脑电图进行了定量功率谱分析（PSA）。PSA显示HD患者的脑电图异常：（i）原始α波功率和α波功率百分比降低；（ii）F3和F4处的原始θ波功率和θ波功率百分比降低；（iii）δ波功率百分比和β波功率百分比增加；（iii）θ波频率降低约1.0Hz。额叶和颞叶脑电图功率测量值以及脑电图振幅降低与神经和认知障碍的严重程度相关。
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