鉴定导致耐头孢他啶肺炎克雷伯菌大规模暴发的TEM-26β-内酰胺酶。
Identification of TEM-26 beta-lactamase responsible for a major outbreak of ceftazidime-resistant Klebsiella pneumoniae.
作者信息
Urban C, Meyer K S, Mariano N, Rahal J J, Flamm R, Rasmussen B A, Bush K
机构信息
Department of Medicine, New York Hospital Medical Center of Queens, Flushing 11355.
出版信息
Antimicrob Agents Chemother. 1994 Feb;38(2):392-5. doi: 10.1128/AAC.38.2.392.
Abstract
An epidemic of nosocomial ceftazidime-resistant Klebsiella pneumoniae was correlated with production of a ceftazidime-hydrolyzing enzyme with an isoelectric point of 5.6 (BMH-1). BMH-1 was encoded on a large transferable plasmid conferring multiple antibiotic resistance. The gene that encodes BMH-1 was identical to the gene that encodes the TEM-26 extended-spectrum beta-lactamase.
摘要
医院内耐头孢他啶肺炎克雷伯菌的流行与一种等电点为5.6的头孢他啶水解酶（BMH-1）的产生有关。BMH-1由一个赋予多重抗生素耐药性的大型可转移质粒编码。编码BMH-1的基因与编码TEM-26超广谱β-内酰胺酶的基因相同。
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本文引用的文献
1
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Antimicrob Agents Chemother. 1993 Sep;37(9):1989-92. doi: 10.1128/AAC.37.9.1989.
2
Nosocomial outbreak of Klebsiella infection resistant to late-generation cephalosporins.
Ann Intern Med. 1993 Sep 1;119(5):353-8. doi: 10.7326/0003-4819-119-5-199309010-00001.
3
Sequences of MGH-1, YOU-1, and YOU-2 extended-spectrum beta-lactamase genes.
Antimicrob Agents Chemother. 1993 Dec;37(12):2760-1. doi: 10.1128/AAC.37.12.2760.
4
Effect of fructose and other carbohydrates on the surface properties, lipoteichoic acid production, and extracellular proteins of Streptococcus mutans Ingbritt grown in continuous culture.
Infect Immun. 1981 Jan;31(1):78-87. doi: 10.1128/iai.31.1.78-87.1981.
5
Extended broad-spectrum beta-lactamases conferring transferable resistance to newer beta-lactam agents in Enterobacteriaceae: hospital prevalence and susceptibility patterns.
Rev Infect Dis. 1988 Jul-Aug;10(4):867-78. doi: 10.1093/clinids/10.4.867.
6
Variations between the nucleotide sequences of Tn1, Tn2, and Tn3 and expression of beta-lactamase in Pseudomonas aeruginosa and Escherichia coli.
J Bacteriol. 1987 Feb;169(2):913-6. doi: 10.1128/jb.169.2.913-916.1987.
7
Effective cooling allows sonication to be used for liberation of beta-lactamases from gram negative bacteria.
J Antimicrob Chemother. 1989 Jul;24(1):82-4. doi: 10.1093/jac/24.1.82.
8
Extended-spectrum beta-lactamases.
Antimicrob Agents Chemother. 1989 Aug;33(8):1131-6. doi: 10.1128/AAC.33.8.1131.
9
Classification of beta-lactamases: groups 2c, 2d, 2e, 3, and 4.
Antimicrob Agents Chemother. 1989 Mar;33(3):271-6. doi: 10.1128/AAC.33.3.271.
10
Classification of beta-lactamases: groups 1, 2a, 2b, and 2b'.
Antimicrob Agents Chemother. 1989 Mar;33(3):264-70. doi: 10.1128/AAC.33.3.264.
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