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供体卵子和胚胎在人类不孕症治疗中的应用。

The use of donor eggs and embryos in the management of human infertility.

作者信息

Leeton J, Trounson A, Wood C

出版信息

Aust N Z J Obstet Gynaecol. 1984 Nov;24(4):265-70. doi: 10.1111/j.1479-828x.1984.tb01508.x.

DOI:10.1111/j.1479-828x.1984.tb01508.x
PMID:6398696
Abstract

The use of donor eggs and embryos is indicated in those infertility cases where the recipient's eggs are either absent, unavailable or inappropriate for in vitro fertilization (IVF) and embryo transfer (ET) programmes. Donor eggs may be fertilized by either the sperm of the recipient's husband (donor egg programme) or by donor sperm (donor embryo programme), in vitro or in vivo and may be transferred as either fresh or frozen-thawed embryos. Human pregnancies and livebirths have recently been reported following the donation of embryos fertilized both in vitro and in vivo. The development of this new technique will allow the achievement of normal pregnancy in infertile women who hitherto had no possible chance of pregnancy.

摘要

在那些不育病例中,如果受体的卵子不存在、无法获取或不适用于体外受精(IVF)和胚胎移植(ET)程序,就需要使用供体卵子和胚胎。供体卵子可以通过受体丈夫的精子(供体卵子程序)或供体精子(供体胚胎程序)进行体外或体内受精,并且可以作为新鲜胚胎或冷冻解冻胚胎进行移植。最近有报道称,体外和体内受精的胚胎捐赠后都实现了人类怀孕和活产。这项新技术的发展将使迄今没有怀孕可能的不育女性能够实现正常怀孕。

相似文献

1
The use of donor eggs and embryos in the management of human infertility.供体卵子和胚胎在人类不孕症治疗中的应用。
Aust N Z J Obstet Gynaecol. 1984 Nov;24(4):265-70. doi: 10.1111/j.1479-828x.1984.tb01508.x.
2
Outcome of donor versus husband insemination in couples with unexplained infertility treated by in vitro fertilization and embryo transfer.体外受精与胚胎移植治疗的不明原因不孕夫妇中供体授精与丈夫授精的结局
Fertil Steril. 1994 Jun;61(6):1088-91. doi: 10.1016/s0015-0282(16)56761-2.
3
Pregnancy established in an infertile patient after transfer of a donated embryo fertilised in vitro.在体外受精的捐赠胚胎移植后,一名不孕患者成功受孕。
Br Med J (Clin Res Ed). 1983 Mar 12;286(6368):835-8. doi: 10.1136/bmj.286.6368.835.
4
Treatment of male infertility and idiopathic failure to fertilize in vitro with under zona insemination and direct egg injection.采用透明带下授精和直接卵内注射治疗男性不育症及特发性体外受精失败。
Am J Obstet Gynecol. 1993 Aug;169(2 Pt 1):324-30; discussion 330-2. doi: 10.1016/0002-9378(93)90083-u.
5
Pregnancy established in an infertile patient after transfer of an embryo fertilized in vitro where the oocyte was donated by the sister of the recipient.在一名不孕患者接受体外受精胚胎移植后成功怀孕,该胚胎的卵母细胞由受者的姐妹捐赠。
J In Vitro Fert Embryo Transf. 1986 Dec;3(6):379-82. doi: 10.1007/BF01133252.
6
Guidelines for the number of embryos to transfer following in vitro fertilization No. 182, September 2006.体外受精后胚胎移植数量指南,2006年9月,第182号
Int J Gynaecol Obstet. 2008 Aug;102(2):203-16. doi: 10.1016/j.ijgo.2008.01.007.
7
In-vitro fertilization with husband and donor sperm in patients with previous fertilization failures using husband sperm.对于既往使用丈夫精子受精失败的患者,采用丈夫精子与供体精子进行体外受精。
Hum Reprod. 1988 Jan;3(1):105-8. doi: 10.1093/oxfordjournals.humrep.a136638.
8
The sharing of eggs by infertile women who are trying to conceive themselves with an egg recipient for financial advantages does not jeopardize the donor's chance of conceiving.试图自行受孕的不孕女性为获取经济利益而将卵子分享给卵子接受者,这并不会危及捐赠者的受孕机会。
Clin Exp Obstet Gynecol. 2012;39(4):432-3.
9
Egg-sharing in assisted conception: ethical and practical considerations.辅助生殖中的卵子共享:伦理与实际考量
Hum Reprod. 1996 May;11(5):1126-31. doi: 10.1093/oxfordjournals.humrep.a019310.
10
Fresh versus frozen thawed semen for initial and late insemination in IVF cycles.新鲜精液与冷冻解冻精液用于体外受精周期的首次和晚期授精
Eur J Obstet Gynecol Reprod Biol. 1991 Nov 26;42(2):115-7. doi: 10.1016/0028-2243(91)90171-g.

引用本文的文献

1
Attitude towards assisted reproductive technology: acceptance of donors eggs, sperms, and embryos as treatment of human infertility: a systematic review and meta-analysis.对辅助生殖技术的态度:接受供体卵子、精子和胚胎作为人类不孕不育治疗的方法:系统评价和荟萃分析。
Reprod Health. 2024 Jan 23;21(1):10. doi: 10.1186/s12978-024-01741-0.
2
Subcutaneous estradiol pellets for endometrial preparation in donor oocyte recipients with a poor endometrial response.皮下注射雌二醇微丸用于子宫内膜反应不良的供体卵母细胞受体的子宫内膜准备。
J Assist Reprod Genet. 1997 Mar;14(3):139-44. doi: 10.1007/BF02766129.
3
Pregnancy established in an infertile patient after transfer of an embryo fertilized in vitro where the oocyte was donated by the sister of the recipient.
在一名不孕患者接受体外受精胚胎移植后成功怀孕,该胚胎的卵母细胞由受者的姐妹捐赠。
J In Vitro Fert Embryo Transf. 1986 Dec;3(6):379-82. doi: 10.1007/BF01133252.
4
Attitudes toward egg donation of thirty-four infertile women who donated during their in vitro fertilization treatment.34名在体外受精治疗期间进行卵子捐赠的不孕女性对卵子捐赠的态度。
J In Vitro Fert Embryo Transf. 1986 Dec;3(6):374-8. doi: 10.1007/BF01133251.
5
Pregnancy results following embryo transfer in women receiving low-dosage variable-length estrogen replacement therapy for premature ovarian failure.接受低剂量可变长度雌激素替代疗法治疗卵巢早衰的女性胚胎移植后的妊娠结果。
J In Vitro Fert Embryo Transf. 1989 Aug;6(4):232-5. doi: 10.1007/BF01132871.