• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

脑膜炎球菌和大肠杆菌荚膜多糖对人和犬血小板体外聚集的影响。

Effects of meningococcal and Escherichia coli capsular polysaccharides on human and dog platelet aggregation in vitro.

作者信息

Johnsson H, Niklasson P M

出版信息

J Clin Pathol. 1976 May;29(5):438-40. doi: 10.1136/jcp.29.5.438.

DOI:10.1136/jcp.29.5.438
PMID:819463
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC476083/
Abstract

Highly purified capsular polysaccharides from groups A, B, and C meningococci and from two strains of Escherichia coli did not aggregate human or dog platelets in vitro. Nor was there any detectable effect on platelet aggregation induced by adenosine diphosphate (ADP), epinephrine, or collagen. The results do not support the hypothesis that capsular polysaccharides are involved in the pathogenesis of thrombocytopenia often seen in severe infections with these bacteria.

摘要

来自A、B和C群脑膜炎球菌以及两株大肠杆菌的高度纯化荚膜多糖,在体外不会使人类或犬类血小板聚集。对于由二磷酸腺苷(ADP)、肾上腺素或胶原蛋白诱导的血小板聚集,也未检测到任何影响。这些结果并不支持以下假说:荚膜多糖参与了这些细菌严重感染时常见的血小板减少症的发病机制。

相似文献

1
Effects of meningococcal and Escherichia coli capsular polysaccharides on human and dog platelet aggregation in vitro.脑膜炎球菌和大肠杆菌荚膜多糖对人和犬血小板体外聚集的影响。
J Clin Pathol. 1976 May;29(5):438-40. doi: 10.1136/jcp.29.5.438.
2
[Platelet function in the dog].[犬的血小板功能]
Boll Soc Ital Biol Sper. 1981 Mar 30;57(6):698-704.
3
Platelet dysfunction associated with immune-mediated thrombocytopenia in dogs.
J Vet Intern Med. 1994 Sep-Oct;8(5):323-7. doi: 10.1111/j.1939-1676.1994.tb03244.x.
4
In vitro inhibition of endotoxin induced platelet aggregation with hydrocortisone sodium succinate (Solu-Cortef).氢化可的松琥珀酸钠(氢化可的松琥钠,Solu-Cortef)对内毒素诱导的血小板聚集的体外抑制作用
Scand J Haematol. 1975 Aug;15(1):35-44. doi: 10.1111/j.1600-0609.1975.tb01053.x.
5
[Potentiating effect of some fatty acids on platelet aggregation induced with ADP, collagen and 1-epinephrine].[某些脂肪酸对由二磷酸腺苷、胶原和肾上腺素诱导的血小板聚集的增强作用]
Boll Soc Ital Biol Sper. 1980 Mar 30;56(6):569-75.
6
Platelet monoamine oxidase and epinephrine-induced platelet aggregation.血小板单胺氧化酶与肾上腺素诱导的血小板聚集
Thromb Haemost. 1978 Aug 31;40(1):37-42.
7
[Action in vitro of isoxsurprine on platelet aggregation induced by ADP, adrenaline and collagen].[异舒普林对ADP、肾上腺素和胶原诱导的血小板聚集的体外作用]
Boll Soc Ital Biol Sper. 1974 Sep 15;50(17):1385-90.
8
[Action of ethacrynic acid on vitro in platelet aggregation induced by ADP, adrenaline or collagen].[依他尼酸对体外由二磷酸腺苷、肾上腺素或胶原诱导的血小板聚集的作用]
Boll Soc Ital Biol Sper. 1974 Sep 15;50(17):1397-42.
9
[Platelet aggregation induced by adenosine diphosphate, collagen and adrenaline in human platelet subpopulations].[二磷酸腺苷、胶原蛋白和肾上腺素诱导的人血小板亚群中的血小板聚集]
Quad Sclavo Diagn. 1987 Sep;23(3):331-40.
10
[Action of furosemide on vitro in platelet aggregation by ADP, adrenaline or collagen].[呋塞米对体外血小板由二磷酸腺苷、肾上腺素或胶原诱导的聚集作用]
Boll Soc Ital Biol Sper. 1974 Sep 15;50(17):1391-6.

本文引用的文献

1
THE AGGREGATION OF HUMAN PLATELETS BY BACTERIAL ENDOTOXIN.细菌内毒素对人血小板的凝集作用。
J Lab Clin Med. 1965 Aug;66:245-52.
2
THE SHWARTZMAN REACTION: PATHOGENETIC MECHANISMS AND CLINICAL MANIFESTATIONS.施瓦茨曼反应:发病机制与临床表现
Annu Rev Med. 1965;16:135-68. doi: 10.1146/annurev.me.16.020165.001031.
3
Aggregation of blood platelets by adenosine diphosphate and its reversal.二磷酸腺苷引起的血小板聚集及其逆转
Nature. 1962 Jun 9;194:927-9. doi: 10.1038/194927b0.
4
Mechanisms of the hemodynamic effects of endotoxin.内毒素血流动力学效应的机制。
Physiol Rev. 1960 Apr;40:245-79. doi: 10.1152/physrev.1960.40.2.245.
5
The quantitation of platelet aggregation induced by four compounds: a study in relation to myocardial infarction.
Thromb Diath Haemorrh. 1966 Dec 1;16(3):752-67.
6
Changes in the blood coagulation system associated with septicemia.与败血症相关的血液凝固系统变化。
N Engl J Med. 1968 Oct 17;279(16):851-6. doi: 10.1056/NEJM196810172791603.
7
Human immunity to the meningococcus. 3. Preparation and immunochemical properties of the group A, group B, and group C meningococcal polysaccharides.人类对脑膜炎球菌的免疫力。3. A 群、B 群和 C 群脑膜炎球菌多糖的制备及免疫化学性质。
J Exp Med. 1969 Jun 1;129(6):1349-65. doi: 10.1084/jem.129.6.1349.
8
Effects of a variety of endotoxins on human and rabbit platelet function.
Thromb Diath Haemorrh. 1971 Dec 31;26(3):467-73.
9
Infection and disseminated intravascular coagulation.
Medicine (Baltimore). 1971 Jul;50(4):237-58. doi: 10.1097/00005792-197107000-00001.
10
Endotoxin and endotoxemia.内毒素与内毒素血症
N Engl J Med. 1973 Jun 14;288(24):1297-8. doi: 10.1056/NEJM197306142882411.