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大肠杆菌中DNA损伤诱导型dinD基因等同于pyrE上游的orfY。

The DNA damage-inducible dinD gene of Escherichia coli is equivalent to orfY upstream of pyrE.

作者信息

Lundegaard C, Jensen K F

机构信息

Department of Biological Chemistry, University of Copenhagen, Denmark.

出版信息

J Bacteriol. 1994 Jun;176(11):3383-5. doi: 10.1128/jb.176.11.3383-3385.1994.

Abstract

The DNA damage-inducible gene dinD, originally identified by Kenyon and Walker (C. J. Kenyon and G. C. Walker, Proc. Natl. Acad. Sci. USA 77:2819-2823, 1980) by selection of the dinD::MudI (Ap lac) fusion, is shown here to be equivalent to the open reading frame orfY near pyrE. The evidence for identity between the two genes includes results from P1 transduction, Southern hybridization, and cloning and sequencing of the dinD fusion. No data were obtained that reveal any hints about the function of the dinD gene.

摘要

DNA损伤诱导基因dinD最初由凯尼恩和沃克(C. J. 凯尼恩和G. C. 沃克,《美国国家科学院院刊》77:2819 - 2823,1980年)通过筛选dinD::MudI(Ap lac)融合体鉴定出来,此处显示它等同于pyrE附近的开放阅读框orfY。这两个基因相同的证据包括P1转导、Southern杂交以及dinD融合体的克隆和测序结果。未获得任何揭示dinD基因功能线索的数据。

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