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新生大鼠单眼摘除诱导的初级视皮层活动变化:一项电生理和放射自显影研究

Modification in primary visual cortical activity of rat induced by neonatal monocular enucleation, an electrophysiological and autoradiographic study.

作者信息

Toldi J, Rojik I, Fehér O

机构信息

Department of Comparative Physiology, József Attila University, Szeged, Hungary.

出版信息

Acta Physiol Hung. 1993;81(2):175-81.

PMID:8197873
Abstract

Mononuclear enucleation was performed in rats at birth. The animals were raised and from the age of 3 months the evoked activity was tested in the contralateral visual cortex both by mapping of evoked potentials and autoradiography. It was found that monocular enucleation changed the distribution of evoked activity characteristically. The focus of activity shifted laterally and restricted itself to the binocular part of the primary visual cortex (Oc1B), while, in the medial part of it (Oc1M) hardly any evoked activity or labelled neurons were found

摘要

在大鼠出生时进行单眼摘除。饲养这些动物,从3个月大开始,通过诱发电位图谱和放射自显影术对其对侧视觉皮层的诱发活动进行测试。结果发现,单眼摘除会以特征性方式改变诱发活动的分布。活动焦点向外侧移动,并局限于初级视觉皮层的双眼部分(Oc1B),而在其内侧部分(Oc1M)几乎未发现任何诱发活动或标记神经元。

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