Kosaka K
Department of Psychiatry, Yokohama City University School of Medicine, Japan.
J Neurol Neurosurg Psychiatry. 1994 May;57(5):594-6. doi: 10.1136/jnnp.57.5.594.
The term "diffuse neurofibrillary tangles with calcification" (DNTC) is proposed for a new form of presenile dementia. It is characterised by slowly progressive cortical dementia in the presenium, localised temporal or temporofrontal lobar atrophy, numerous neurofibrillary tangles widespread in the cerebral cortex, and pronounced calcareous deposits; 16 cases of DNTC, have been reported.
“伴有钙化的弥漫性神经原纤维缠结”(DNTC)这一术语被用于一种新型早老性痴呆。其特征为早老期缓慢进展的皮质性痴呆、局限性颞叶或颞额叶萎缩、大脑皮质广泛分布的大量神经原纤维缠结以及明显的钙质沉积;已报道了16例DNTC病例。