Haaskjold E, Ohrström A, Uusitalo R J, Krootila K, Sandvig K U, Sönne H, Mahlberg K
Rikshospitalet, Department of Ophthalmology, University of Oslo, Norway.
J Cataract Refract Surg. 1994 Mar;20(2):150-3. doi: 10.1016/s0886-3350(13)80155-1.
A randomized, prospective, multicenter study evaluated the efficacy and safety of using collagen shields to deliver drugs after cataract surgery. Collagen shields saturated with an antibiotic and a steroid were placed in 90 eyes postoperatively. A control group of 93 eyes received the same drugs through a peribulbar/retrobulbar injection. One day after surgery, the shield group had significantly less corneal edema, conjunctival hemorrhaging, and postoperative pain and fewer corneal opacities. All symptoms except the conjunctival hemorrhaging disappeared by day seven. Our study suggests that using collagen shields for drug delivery after cataract surgery decreases tissue damage and increases patient comfort without adverse side effects.
一项随机、前瞻性、多中心研究评估了白内障手术后使用胶原盾输送药物的疗效和安全性。90只眼睛在术后放置了用抗生素和类固醇饱和的胶原盾。93只眼睛的对照组通过球周/球后注射接受相同的药物。术后一天，胶原盾组的角膜水肿、结膜出血和术后疼痛明显减轻，角膜混浊也较少。除结膜出血外，所有症状在术后七天内消失。我们的研究表明，白内障手术后使用胶原盾输送药物可减少组织损伤，增加患者舒适度，且无不良副作用。
