一名患有横纹肌溶解症的精神分裂症患者发生水中毒。

Water intoxication in a schizophrenic patient with rhabdomyolysis.

作者信息

Akasaki Y, Nagatomo I, Akasaki Y, Nomaguchi M, Akasaki Y, Matsumoto K

机构信息

Department of Neuropsychiatry, Faculty of Medicine, Kagoshima University, Japan.

出版信息

Jpn J Psychiatry Neurol. 1993 Dec;47(4):843-6. doi: 10.1111/j.1440-1819.1993.tb01831.x.

DOI:10.1111/j.1440-1819.1993.tb01831.x

PMID:8201794

Abstract

We report a case of water intoxication in a 54-year-old female schizophrenic patient with rhabdomyolysis. She had been admitted to a mental hospital, and treated with spiperone 6 mg daily. On August 3, 1992, the coma following a convulsion occurred. Laboratory data initially showed marked hyponatremia and hypochloremia with decreased serum potassium, and a gradual increase in serum creatine phosphokinase (CPK). The elevation in serum CPK with marked hyponatremia observed in the present patient was probably caused by excessive drinking of water. In this patient, the CPK elevation revealed the rhabdomyolysis.

摘要

我们报告一例54岁患有横纹肌溶解症的女性精神分裂症患者发生水中毒的病例。她入住一家精神病院，每日接受6毫克舒必利治疗。1992年8月3日，患者在抽搐后陷入昏迷。实验室检查最初显示明显低钠血症、低氯血症伴血清钾降低，血清肌酸磷酸激酶（CPK）逐渐升高。本患者出现的血清CPK升高伴明显低钠血症可能是由于过量饮水所致。在该患者中，CPK升高提示横纹肌溶解症。