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通过在补液中添加小剂量胰岛素治疗儿童糖尿病酮症。

Diabetic ketosis in children treated by adding low-dose insulin to rehydrating fluid.

作者信息

Malleson P N

出版信息

Arch Dis Child. 1976 May;51(5):373-6. doi: 10.1136/adc.51.5.373.

Abstract

Four children with severe diabetic ketosis were successfully treated with a regimen of low-dose intermittent insulin infusions in the rehydrating fluid. The children all rapidly regained consciousness and tolerated oral fluids within 12 hours of admission. Hypoglycaemia and hypokalaemia, both complications of conventional large dose insulin treatment, did not occur. Plasma insulin levels obtained by this method were maintained in the optimum range recommended by Sönksen et al. (1972).

摘要

4名患有严重糖尿病酮症的儿童通过在补液中采用小剂量间歇性胰岛素输注方案成功得到治疗。这些儿童在入院后12小时内均迅速恢复意识并能耐受口服补液。传统大剂量胰岛素治疗的并发症低血糖和低钾血症均未发生。通过这种方法测得的血浆胰岛素水平维持在Sönksen等人(1972年)推荐的最佳范围内。

引用本文的文献

1
Insulin regimens for diabetic ketoacidosis.
Br Med J. 1977 Feb 12;1(6058):405-6. doi: 10.1136/bmj.1.6058.405-a.

本文引用的文献

1
Treatment of severe diabetes mellitus by insulin infusion.
Br Med J. 1974 Jun 29;2(5921):691-4. doi: 10.1136/bmj.2.5921.691.
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Treatment of diabetic coma with continuous low-dose infusion of insulin.
Br Med J. 1974 Jun 29;2(5921):687-90. doi: 10.1136/bmj.2.5921.687.
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Continuous intravenous infusion of small doses of insulin in treatment of diabetic ketoacidosis.
Br Med J. 1974 Jun 29;2(5921):694-8. doi: 10.1136/bmj.2.5921.694.
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Small doses of intramuscular insulin in the treatment of diabetic "coma".
Lancet. 1973 Sep 8;2(7828):515-22. doi: 10.1016/s0140-6736(73)92346-5.
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Growth-hormone and cortisol responses to insulin infusion in patients with diabetes mellitus.
Lancet. 1972 Jul 22;2(7769):155-9. doi: 10.1016/s0140-6736(72)91328-1.
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Immediate metabolic response to a low dose of insulin in children presenting with diabetes.
Arch Dis Child. 1975 May;50(5):373-8. doi: 10.1136/adc.50.5.373.
7
Diabetic crises in children treated with small doses of intramuscular insulin.
Br Med J. 1975 Jan 11;1(5949):59-61. doi: 10.1136/bmj.1.5949.59.

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