Malleson P N
Arch Dis Child. 1976 May;51(5):373-6. doi: 10.1136/adc.51.5.373.
Four children with severe diabetic ketosis were successfully treated with a regimen of low-dose intermittent insulin infusions in the rehydrating fluid. The children all rapidly regained consciousness and tolerated oral fluids within 12 hours of admission. Hypoglycaemia and hypokalaemia, both complications of conventional large dose insulin treatment, did not occur. Plasma insulin levels obtained by this method were maintained in the optimum range recommended by Sönksen et al. (1972).
4名患有严重糖尿病酮症的儿童通过在补液中采用小剂量间歇性胰岛素输注方案成功得到治疗。这些儿童在入院后12小时内均迅速恢复意识并能耐受口服补液。传统大剂量胰岛素治疗的并发症低血糖和低钾血症均未发生。通过这种方法测得的血浆胰岛素水平维持在Sönksen等人（1972年）推荐的最佳范围内。
