Vidović A, Janković G, Suvajdzić N, Colović M
Institut za hematologiju UKC, Beograd.
Srp Arh Celok Lek. 1993 Jan-Feb;121(1-2):48-9.
A patient with Ph1(Philadelphia chromosome) positive chronic granulocytic leukemia and extramedullary blast transformation (crisis) in lymph nodes of the neck and axillae which appeared after a 4-year treatment with busulfan, is presented. Biopsy of lymph node and histopathological examination showed lymphoblastic infiltration. The patient was treated with radiotherapy and chemotherapy with protocol COP. He survived 7 months and expired due to renal insufficiency.
报告一例患有Ph1（费城染色体）阳性慢性粒细胞白血病的患者，其在接受白消安治疗4年后出现颈部和腋窝淋巴结髓外原始细胞转化（危象）。淋巴结活检及组织病理学检查显示淋巴细胞浸润。该患者接受了放疗及采用COP方案的化疗。他存活了7个月，最终因肾功能不全死亡。
