Ohta N, Fukase S, Aoyagi M, Koike Y, Fukase Y, Sendo F
Department of Otolaryngology, Yamagata University School of Medicine, Japan.
Acta Otolaryngol Suppl. 1994;511:208-13. doi: 10.3109/00016489409128334.
The palatine tonsil is the most important element of Waldeyer's ring as a defense mechanism against various microorganisms. The neutrophils are the initial active participants in bacterial infection and inflammation, but their interaction with other cellular participants is poorly understood. To clarify this point, the effects of culture supernatant from human tonsillar cells on the peripheral neutrophil function were investigated. Supernatants from tonsillar cells were incubated in the presence or absence of streptococcal preparation (OK-432) enhanced chemiluminescence, adherence, phagocytosis, chemotaxis, and superoxide production of human peripheral neutrophils. The results suggest that tonsils play an important role in the regulation of neutrophil function.
腭扁桃体是瓦尔代尔环中作为抵御各种微生物的防御机制的最重要组成部分。中性粒细胞是细菌感染和炎症中的初始活跃参与者，但其与其他细胞参与者的相互作用却知之甚少。为阐明这一点，研究了人扁桃体细胞培养上清液对周围中性粒细胞功能的影响。扁桃体细胞的上清液在有或无链球菌制剂（OK-432）存在的情况下孵育，可增强人外周中性粒细胞的化学发光、黏附、吞噬、趋化性和超氧化物生成。结果表明，扁桃体在中性粒细胞功能的调节中起重要作用。
