Kato I, Ishikawa M, Nakamura T, Watanabe J, Harada K, Kanayama R, Aoyagi M, Koike Y
Department of Otolaryngology, St. Marianna University School of Medicine, Kanagawa, Japan.
Acta Otolaryngol Suppl. 1994;511:99-103. doi: 10.3109/00016489409128310.
A quantitative assessment of the influence of aging on optokinetic nystagmus (OKN) was investigated using 50 normal adults in ages ranging from 30 to 70 years. In linear stimulus-induced OKN, a statistically significant difference was demonstrated in slow-phase OKN velocity only between the 30-59 year old age group and the 70-79-year-old age group, when OKN stimulus was more than 60 degrees/s. Step stimulus-induced OKN was investigated in the same age groups in order to compare aging effects upon slow-phase OKN velocity. No statistically significant difference was found in slow-phase OKN velocity between younger age groups and the oldest age group. There was no significant difference in fast-phase velocity among the age groups. Thus, step-induced OKN has a wider clinical application than linear stimulus-induced OKN.
使用50名年龄在30至70岁之间的正常成年人，对衰老对视动性眼球震颤（OKN）的影响进行了定量评估。在直线刺激诱发的OKN中，当OKN刺激超过60度/秒时，仅在30至59岁年龄组和70至79岁年龄组之间，慢相OKN速度存在统计学上的显著差异。为了比较衰老对慢相OKN速度的影响，对相同年龄组进行了阶梯刺激诱发的OKN研究。在较年轻年龄组和最年长年龄组之间，慢相OKN速度未发现统计学上的显著差异。各年龄组之间快相速度无显著差异。因此，阶梯诱发的OKN比直线刺激诱发的OKN具有更广泛的临床应用。
