Paganini-Hill A, Hsu G
Department of Preventive Medicine, University of Southern California School of Medicine, Los Angeles 90031.
Am J Public Health. 1994 Jun;84(6):992-5. doi: 10.2105/ajph.84.6.992.
Smoking cessation decreases mortality among the elderly. Participants in the Leisure World Cohort Study initiated in 1981 were followed until death or January 1, 1991. The 8869 women and 4999 men (median age = 73 years at initial survey) contributed 105,952 person-years of follow-up; 4002 had died. All-cause mortality rates were highest among current smokers; compared with never smokers the age-adjusted relative risks (and 95% confidence intervals) were 1.67 (1.46, 1.92) for women and 1.95 (1.66, 2.30) for men. Current smokers had increased risks of coronary heart disease, other cardiovascular disease, and cancer. Risk of death from smoking-related cancers continued to be high among former smokers, although lower than the risk among current smokers. Relative risks of mortality from cancer and cardiovascular disease increased with the number of cigarettes smoked per day and with a decreasing number of years since cessation of smoking.
戒烟可降低老年人的死亡率。对1981年启动的休闲世界队列研究中的参与者进行随访,直至其死亡或1991年1月1日。8869名女性和4999名男性(初次调查时年龄中位数为73岁)提供了105,952人年的随访数据;4002人已经死亡。全因死亡率在当前吸烟者中最高;与从不吸烟者相比,年龄调整后的相对风险(及95%置信区间)女性为1.67(1.46, 1.92),男性为1.95(1.66, 2.30)。当前吸烟者患冠心病、其他心血管疾病和癌症的风险增加。尽管已戒烟者死于吸烟相关癌症的风险低于当前吸烟者,但仍然很高。癌症和心血管疾病的死亡相对风险随着每日吸烟量的增加以及戒烟后年限的减少而增加。