Grekova T I, Reznikov K M, Vinokurova O V, Kireeva A A, Taratinova T I, Nikolaevskiĭ V A, Shchetinkina N A
Eksp Klin Farmakol. 1994 Mar-Apr;57(2):24-6.
Five models of arrhythmias (aconitine-, calcium chloride- and low-sodium-induced models on rats, coronary artery ligation and reperfusion in dogs) were used to study the antiarrhythmic and antifibrillatory effects. The latters were not inferior to those shown by the well-known antiarrhythmics. The mechanisms of the action of dalargin are discussed in the paper.
采用五种心律失常模型(大鼠乌头碱、氯化钙和低钠诱导模型,犬冠状动脉结扎及再灌注模型)研究其抗心律失常和抗纤颤作用。这些作用不低于知名抗心律失常药物所表现出的作用。本文讨论了达拉美丁的作用机制。