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癫痫,我们这个时代创伤的产物。

Epilepsy, a product of trauma in our time.

作者信息

Caveness W F

出版信息

Epilepsia. 1976 Jun;17(2):207-15. doi: 10.1111/j.1528-1157.1976.tb03398.x.

Abstract

Using data obtained by the National Center for Health Statistics through household interviews, an estimate of 8,100,000 cases of head injury was determined for the civilian population of the United States in 1974. Excluding contusions and lacerations of the scalp, face, and neck; there remained 1,900,000 with concussion, skull fractures, intracranial hemorrhage, cerebral laceration, or other intracranial injury. Extrapolating from the military experience with craniocerebral trauma admittedly a rough approximation, it is estimated that in 30% of this latter group one more seizures will develop. Both severity of the injury and the predisposition of the injured are thought to play a part in the occurrence of seizures, with the predisposition playing the dominant role in the persistence of seizures. The following gradation of posttraumatic epilepsy is predicted for the 1,900,000 with the greater implication of brain damage: 1,340,000 will never have a seizure; 560,000 will develop one or more attacks, most of which will begin in 1974, 1975, or 1976. In 280,000 of these, the attacks will be transient and of little consequence. In an equal number, the attacks will require medical attention, and in some 140,000 the seizures will be intractable to therapy. This latter group represents 7% of the 1,900,000 cases. Attention is directed to the practical problems in the control of carniocerebral trauma and of posttraumatic epilepsy.

摘要

利用美国国家卫生统计中心通过家庭访谈获得的数据,确定了1974年美国平民人口中头部受伤病例估计为810万例。排除头皮、面部和颈部的挫伤和裂伤后,仍有190万人患有脑震荡、颅骨骨折、颅内出血、脑裂伤或其他颅内损伤。根据颅脑创伤的军事经验推断(诚然这是一个粗略的估计),估计后一组中有30%的人会再发生一次癫痫发作。损伤的严重程度和受伤者的易感性都被认为在癫痫发作的发生中起作用,而易感性在癫痫发作的持续中起主导作用。对于这190万脑损伤影响更大的人,预计创伤后癫痫的分级如下:134万人永远不会发作;56万人会发作一次或多次,其中大多数将在1974年、1975年或1976年开始。在这些人中,28万人的发作将是短暂的,影响不大。人数相同的另一组发作需要医疗护理,约14万人的癫痫发作将难以治疗。后一组占190万病例的7%。人们将注意力转向控制颅脑创伤和创伤后癫痫的实际问题。

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