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与布线规范以及电场和磁场相关的人类健康影响的流行病学研究中的问题与重点。

Problems and priorities in epidemiologic research on human health effects related to wiring code and electric and magnetic fields.

作者信息

Siemiatycki J

机构信息

Epidemiology Research Unit, Institut Armand-Frappier, Laval-des-Rapides, Quebec, Canada.

出版信息

Environ Health Perspect. 1993 Dec;101 Suppl 4(Suppl 4):135-41. doi: 10.1289/ehp.93101s4135.

DOI:10.1289/ehp.93101s4135
PMID:8206022
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1519715/
Abstract

Because of a reported excess of cancers among children living near power lines, there is some concern that electric and magnetic fields (EMFs) induced by electric power sources may affect human health, and this possibility has provoked considerable controversy. The scientific question of whether there are such health effects is far from resolved. Building upon a set of detailed reviews of the available evidence, this paper proposes research priorities and places particular emphasis on epidemiologic research. The most pressing need is to verify the validity of the claim that childhood cancer risk is affected by the type of wiring code in the vicinity of the household. More useful work can be done to verify this in the areas in which such studies have already been carried out, and additional studies should be done elsewhere. Methodological investigation of the interrelationships among different measures and proxies for EMF is needed, and this could feed back to influence the type of EMF measures used in epidemiologic studies. Studies of cancer among adults in relation to EMFs in the work place are needed. Of lower priority are studies of adverse reproductive outcomes in relation to parental EMF exposure and studies of the neurobehavioral impact of chronic EMF exposure. This article also discusses the structural impediments of conducting environmental epidemiology research and argues that bold, large-scale epidemiologic monitoring systems are needed. There is a discussion of the interface between epidemiology and public policy in a topic area as controversial as EMFs.

摘要

由于有报道称居住在输电线附近的儿童患癌症的比例过高,人们担心电源产生的电场和磁场(EMF)可能会影响人类健康,这种可能性引发了相当大的争议。关于是否存在此类健康影响的科学问题远未得到解决。基于对现有证据的一系列详细综述,本文提出了研究重点,并特别强调了流行病学研究。最紧迫的需求是核实关于儿童癌症风险受家庭附近布线规范类型影响这一说法的真实性。在已经开展此类研究的地区,可以进行更多有用的工作来核实这一点,并且应该在其他地方开展更多研究。需要对EMF的不同测量方法和替代指标之间的相互关系进行方法学研究,这可能会反馈影响流行病学研究中使用的EMF测量类型。需要开展关于成年人在工作场所接触EMF与癌症关系的研究。与父母接触EMF相关的不良生殖结局研究以及慢性EMF暴露对神经行为影响的研究优先级较低。本文还讨论了开展环境流行病学研究的结构障碍,并认为需要大胆、大规模的流行病学监测系统。文中还讨论了在像EMF这样有争议的主题领域中流行病学与公共政策之间的接口问题。

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引用本文的文献

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Health effects of electric and magnetic fields: overview of research recommendations.电场与磁场对健康的影响:研究建议概述。
Environ Health Perspect. 1993 Dec;101(Suppl 4):71-2. doi: 10.1289/ehp.93101s471.

本文引用的文献

1
Biologically based epidemiological studies of electric power and cancer.基于生物学的电力与癌症流行病学研究。
Environ Health Perspect. 1993 Dec;101 Suppl 4(Suppl 4):93-100. doi: 10.1289/ehp.93101s493.
2
Epidemiologic studies of electric and magnetic fields and cancer: strategies for extending knowledge.电场和磁场与癌症的流行病学研究:拓展知识的策略
Environ Health Perspect. 1993 Dec;101 Suppl 4(Suppl 4):83-91. doi: 10.1289/ehp.93101s483.
3
Introduction to power-frequency electric and magnetic fields.工频电场和磁场简介。
Environ Health Perspect. 1993 Dec;101 Suppl 4(Suppl 4):73-81. doi: 10.1289/ehp.93101s473.
4
Assessing human exposure to power-frequency electric and magnetic fields.评估人类对工频电场和磁场的暴露情况。
Environ Health Perspect. 1993 Dec;101 Suppl 4(Suppl 4):121-33. doi: 10.1289/ehp.93101s4121.
5
Human adverse reproductive outcomes and electromagnetic field exposures: review of epidemiologic studies.人类不良生殖结局与电磁场暴露:流行病学研究综述
Environ Health Perspect. 1993 Dec;101 Suppl 4(Suppl 4):107-19. doi: 10.1289/ehp.93101s4107.
6
Neurobehavioral effects of power-frequency electromagnetic fields.工频电磁场的神经行为效应。
Environ Health Perspect. 1993 Dec;101 Suppl 4(Suppl 4):101-6. doi: 10.1289/ehp.93101s4101.
7
Electrical wiring configurations and childhood leukemia in Rhode Island.罗德岛的电气布线配置与儿童白血病
Am J Epidemiol. 1980 Apr;111(4):461-2. doi: 10.1093/oxfordjournals.aje.a112924.
8
Electrical wiring configurations and childhood leukemia in Rhode Island.罗德岛的电气布线配置与儿童白血病
Am J Epidemiol. 1980 Mar;111(3):292-6. doi: 10.1093/oxfordjournals.aje.a112899.
9
Discovering carcinogens in the occupational environment: a novel epidemiologic approach.在职业环境中发现致癌物:一种新的流行病学方法。
J Natl Cancer Inst. 1981 Feb;66(2):217-25.
10
50-Hz electromagnetic environment and the incidence of childhood tumors in Stockholm County.斯德哥尔摩郡的50赫兹电磁环境与儿童肿瘤发病率
Bioelectromagnetics. 1986;7(2):191-207. doi: 10.1002/bem.2250070209.