优先与富含C的寡聚单链核酸结合的小鼠蛋白。
Murine protein which binds preferentially to oligo-C-rich single-stranded nucleic acids.
作者信息
Goller M, Funke B, Gehe-Becker C, Kröger B, Lottspeich F, Horak I
机构信息
Institut für Virologie und Immunbiologie, Universität Würzburg, Germany.
出版信息
Nucleic Acids Res. 1994 May 25;22(10):1885-9. doi: 10.1093/nar/22.10.1885.
Abstract
Two single-stranded nucleic acid binding proteins mCBP and mCTBP were identified by means of their binding to a potential recombination hotspot in LTRs of mouse retro-transposons. Both are nuclear proteins of 35 and 55 kDa respectively. mCBP binds preferentially to oligo dC, mCTBP to oligo dCdT. mCBP was purified and its cDNA was isolated and sequenced.
摘要
通过它们与小鼠逆转座子长末端重复序列（LTRs）中一个潜在重组热点的结合，鉴定出了两种单链核酸结合蛋白mCBP和mCTBP。二者均为核蛋白，分子量分别为35 kDa和55 kDa。mCBP优先结合寡聚dC，mCTBP优先结合寡聚dCdT。mCBP被纯化，其cDNA被分离并测序。
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